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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPP6 All Species: 30.3
Human Site: S391 Identified Species: 47.62
UniProt: Q9NZW5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZW5 NP_057531.2 540 61117 S391 G Q A Y K F V S R S E M E A D
Chimpanzee Pan troglodytes XP_001159242 552 62429 S403 G Q A Y K F V S R S E M E A D
Rhesus Macaque Macaca mulatta XP_001096776 582 65885 S433 G Q A Y K F V S R S E M E A D
Dog Lupus familis XP_539479 540 61070 S391 G Q A Y K F V S R S E M E A D
Cat Felis silvestris
Mouse Mus musculus Q9JLB0 553 62612 S404 G Q A Y K F V S R S E M E A D
Rat Rattus norvegicus Q62915 909 103240 P760 P I P H T T R P P K K D E E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507958 540 61012 S391 G Q A Y K F V S R A E M E T D
Chicken Gallus gallus Q5ZJ00 468 52501 T319 F M Y P P P Y T T R P Q K K N
Frog Xenopus laevis NP_001084783 538 60687 S389 G H A Y R F V S R V E M E A D
Zebra Danio Brachydanio rerio Q6P0D7 576 65174 S421 G V E Y H F I S K N L F E A D
Tiger Blowfish Takifugu rubipres P49697 467 52590 P321 P V P H T T R P Q R K G D A N
Fruit Fly Dros. melanogaster Q24210 898 100893 P752 H T T R P A K P E E E N G R S
Honey Bee Apis mellifera XP_391909 602 67965 D452 G K S Y W F I D R E S M E T D
Nematode Worm Caenorhab. elegans P54936 961 108794 P812 P I P H T T R P P R K D E V D
Sea Urchin Strong. purpuratus XP_791632 556 63023 L407 G V E Y H F V L R S D M E Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 92.7 99.6 N.A. 95.8 30 N.A. 96.8 37.7 86.8 37.8 35.3 28.8 42.3 28.6 48.7
Protein Similarity: 100 97.8 92.7 100 N.A. 96.9 42.5 N.A. 99.2 55.3 94.8 55.9 55.5 41.8 63.7 39.9 67.9
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 86.6 0 80 46.6 6.6 6.6 46.6 13.3 60
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 93.3 20 86.6 66.6 40 6.6 66.6 26.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 47 0 0 7 0 0 0 7 0 0 0 54 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 7 14 7 0 74 % D
% Glu: 0 0 14 0 0 0 0 0 7 14 54 0 80 7 0 % E
% Phe: 7 0 0 0 0 67 0 0 0 0 0 7 0 0 0 % F
% Gly: 67 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % G
% His: 7 7 0 20 14 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 14 0 0 0 0 14 0 0 0 0 0 0 0 0 % I
% Lys: 0 7 0 0 40 0 7 0 7 7 20 0 7 7 0 % K
% Leu: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 0 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 60 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 20 % N
% Pro: 20 0 20 7 14 7 0 27 14 0 7 0 0 0 0 % P
% Gln: 0 40 0 0 0 0 0 0 7 0 0 7 0 7 0 % Q
% Arg: 0 0 0 7 7 0 20 0 60 20 0 0 0 7 0 % R
% Ser: 0 0 7 0 0 0 0 54 0 40 7 0 0 0 7 % S
% Thr: 0 7 7 0 20 20 0 7 7 0 0 0 0 14 0 % T
% Val: 0 20 0 0 0 0 54 0 0 7 0 0 0 7 0 % V
% Trp: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 67 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _