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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPP6 All Species: 37.88
Human Site: S276 Identified Species: 59.52
UniProt: Q9NZW5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZW5 NP_057531.2 540 61117 S276 G S A G L I P S Q F L E E K R
Chimpanzee Pan troglodytes XP_001159242 552 62429 S288 G S A G L I P S Q F L E E K R
Rhesus Macaque Macaca mulatta XP_001096776 582 65885 S318 G S A G L I P S Q F L E E K R
Dog Lupus familis XP_539479 540 61070 S276 G S A G L I P S Q F L E E K R
Cat Felis silvestris
Mouse Mus musculus Q9JLB0 553 62612 S289 G S A G L I P S Q F L E E K R
Rat Rattus norvegicus Q62915 909 103240 W645 S K D D H N W W Q G K L E N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507958 540 61012 S276 G S A G L I P S Q F L E E K R
Chicken Gallus gallus Q5ZJ00 468 52501 G207 D D S N W W Q G R V E G S G T
Frog Xenopus laevis NP_001084783 538 60687 S274 G S A G L I P S Q F L E E K R
Zebra Danio Brachydanio rerio Q6P0D7 576 65174 S290 L R A G L I P S K H F Q E R R
Tiger Blowfish Takifugu rubipres P49697 467 52590 V209 P N W W Q G R V E N N A A N F
Fruit Fly Dros. melanogaster Q24210 898 100893 L640 T V G G S A G L I P S P E L Q
Honey Bee Apis mellifera XP_391909 602 67965 S335 G P P G L I P S L E L E E R R
Nematode Worm Caenorhab. elegans P54936 961 108794 N694 P S I G N S S N A Q R S N Q Q
Sea Urchin Strong. purpuratus XP_791632 556 63023 S290 G Q S G L I P S Q D L E E R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 92.7 99.6 N.A. 95.8 30 N.A. 96.8 37.7 86.8 37.8 35.3 28.8 42.3 28.6 48.7
Protein Similarity: 100 97.8 92.7 100 N.A. 96.9 42.5 N.A. 99.2 55.3 94.8 55.9 55.5 41.8 63.7 39.9 67.9
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 100 0 100 53.3 0 13.3 66.6 13.3 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 100 13.3 100 73.3 13.3 20 73.3 33.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 54 0 0 7 0 0 7 0 0 7 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 7 7 0 0 0 0 0 7 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 7 7 60 80 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 47 7 0 0 0 7 % F
% Gly: 60 0 7 80 0 7 7 7 0 7 0 7 0 7 0 % G
% His: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 67 0 0 7 0 0 0 0 0 0 % I
% Lys: 0 7 0 0 0 0 0 0 7 0 7 0 0 47 0 % K
% Leu: 7 0 0 0 67 0 0 7 7 0 60 7 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 7 7 7 0 7 0 7 7 0 7 14 0 % N
% Pro: 14 7 7 0 0 0 67 0 0 7 0 7 0 0 0 % P
% Gln: 0 7 0 0 7 0 7 0 60 7 0 7 0 7 14 % Q
% Arg: 0 7 0 0 0 0 7 0 7 0 7 0 0 20 67 % R
% Ser: 7 54 14 0 7 7 7 67 0 0 7 7 7 0 7 % S
% Thr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % T
% Val: 0 7 0 0 0 0 0 7 0 7 0 0 0 0 0 % V
% Trp: 0 0 7 7 7 7 7 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _