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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPP6 All Species: 27.27
Human Site: S110 Identified Species: 42.86
UniProt: Q9NZW5 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZW5 NP_057531.2 540 61117 S110 C Y D S P P S S P E M N N S S
Chimpanzee Pan troglodytes XP_001159242 552 62429 S110 C Y D S P P S S P E M N N S S
Rhesus Macaque Macaca mulatta XP_001096776 582 65885 S152 C Y D S P P S S P E M N N S S
Dog Lupus familis XP_539479 540 61070 S110 C Y D S P P S S P E M N N S S
Cat Felis silvestris
Mouse Mus musculus Q9JLB0 553 62612 S110 C Y D S P P S S P E M N I P S
Rat Rattus norvegicus Q62915 909 103240 R458 V Y S D E A L R V T P P P T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507958 540 61012 S110 C Y D S P P S S P E M N N S S
Chicken Gallus gallus Q5ZJ00 468 52501 S95 L K L N D K Q S C M V A R I F
Frog Xenopus laevis NP_001084783 538 60687 S110 C Y D S P P S S P E V N S S G
Zebra Danio Brachydanio rerio Q6P0D7 576 65174 P125 S Y D P E L P P L P D D I D D
Tiger Blowfish Takifugu rubipres P49697 467 52590 V98 N D K Q R C S V A R I L H G G
Fruit Fly Dros. melanogaster Q24210 898 100893 R464 V Y G E E A L R V T P P P M V
Honey Bee Apis mellifera XP_391909 602 67965 P168 K E A P P S K P E P S L L A M
Nematode Worm Caenorhab. elegans P54936 961 108794 K268 M L N A D P S K R I S A K E A
Sea Urchin Strong. purpuratus XP_791632 556 63023 E124 N L G S S E F E D H T Q D Y Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 92.7 99.6 N.A. 95.8 30 N.A. 96.8 37.7 86.8 37.8 35.3 28.8 42.3 28.6 48.7
Protein Similarity: 100 97.8 92.7 100 N.A. 96.9 42.5 N.A. 99.2 55.3 94.8 55.9 55.5 41.8 63.7 39.9 67.9
P-Site Identity: 100 100 100 100 N.A. 86.6 13.3 N.A. 100 6.6 80 13.3 6.6 6.6 6.6 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 20 N.A. 100 20 93.3 20 20 6.6 13.3 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 14 0 0 7 0 0 14 0 7 7 % A
% Cys: 47 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 7 54 7 14 0 0 0 7 0 7 7 7 7 7 % D
% Glu: 0 7 0 7 20 7 0 7 7 47 0 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 14 0 0 0 0 0 0 0 0 0 0 7 14 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 7 7 0 14 7 0 % I
% Lys: 7 7 7 0 0 7 7 7 0 0 0 0 7 0 0 % K
% Leu: 7 14 7 0 0 7 14 0 7 0 0 14 7 0 0 % L
% Met: 7 0 0 0 0 0 0 0 0 7 40 0 0 7 7 % M
% Asn: 14 0 7 7 0 0 0 0 0 0 0 47 34 0 0 % N
% Pro: 0 0 0 14 54 54 7 14 47 14 14 14 14 7 0 % P
% Gln: 0 0 0 7 0 0 7 0 0 0 0 7 0 0 0 % Q
% Arg: 0 0 0 0 7 0 0 14 7 7 0 0 7 0 0 % R
% Ser: 7 0 7 54 7 7 60 54 0 0 14 0 7 40 47 % S
% Thr: 0 0 0 0 0 0 0 0 0 14 7 0 0 7 0 % T
% Val: 14 0 0 0 0 0 0 7 14 0 14 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 67 0 0 0 0 0 0 0 0 0 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _