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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BFAR All Species: 25.45
Human Site: Y273 Identified Species: 62.22
UniProt: Q9NZS9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZS9 NP_057645.1 450 52738 Y273 G R S L F L L Y A L K S S P R
Chimpanzee Pan troglodytes XP_001148011 450 52744 Y273 G R S L F L L Y A L K S S P R
Rhesus Macaque Macaca mulatta XP_001107892 450 52805 Y273 G R S L F L L Y A L K S S P R
Dog Lupus familis XP_547118 450 52548 Y273 G R S L F L L Y A L K S S P R
Cat Felis silvestris
Mouse Mus musculus Q8R079 450 52950 Y273 G R S L F L L Y A L K S S P R
Rat Rattus norvegicus Q5PQN2 450 53006 Y273 G R S L F L L Y A L K S S P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516855 331 37501 V166 D I Q Q N S D V A H S L A A F
Chicken Gallus gallus XP_414737 437 51603 L260 P G K S L F L L Y A L K N S P
Frog Xenopus laevis NP_001088347 448 52481 L271 S L F L L Y A L K S S P R L S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784327 488 56535 Y322 G L S T F L S Y T V R E F P R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.2 92.8 N.A. 90 90.2 N.A. 52 79.5 75.7 N.A. N.A. N.A. N.A. N.A. 38.1
Protein Similarity: 100 99.7 99.5 96.8 N.A. 94.8 94.8 N.A. 58.2 87.5 85.7 N.A. N.A. N.A. N.A. N.A. 57.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 13.3 6.6 N.A. N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 70 10 0 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 10 0 70 10 0 0 0 0 0 0 10 0 10 % F
% Gly: 70 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 10 0 60 10 0 0 0 % K
% Leu: 0 20 0 70 20 70 70 20 0 60 10 10 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 10 0 70 10 % P
% Gln: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 60 0 0 0 0 0 0 0 0 10 0 10 0 70 % R
% Ser: 10 0 70 10 0 10 10 0 0 10 20 60 60 10 10 % S
% Thr: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 70 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _