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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP1B
All Species:
26.67
Human Site:
Y4566
Identified Species:
58.67
UniProt:
Q9NZR2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZR2
NP_061027.2
4599
515498
Y4566
N
P
V
Y
A
K
L
Y
M
D
G
Q
N
C
R
Chimpanzee
Pan troglodytes
XP_515817
4636
518955
Y4603
N
P
V
Y
A
K
L
Y
M
D
G
Q
N
C
R
Rhesus Macaque
Macaca mulatta
XP_001117994
4592
514768
Y4559
N
P
V
Y
A
K
L
Y
M
D
G
Q
N
C
R
Dog
Lupus familis
XP_533343
4492
503712
Y4459
N
P
V
Y
A
K
L
Y
M
D
G
Q
N
C
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI18
4599
513616
Y4566
N
P
V
Y
A
K
L
Y
M
D
G
Q
N
C
R
Rat
Rattus norvegicus
P98158
4660
519258
S4632
P
S
L
P
A
K
A
S
K
R
N
L
T
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
Y4510
N
P
V
Y
A
T
L
Y
M
G
A
H
S
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920039
4500
501034
Y4467
N
P
M
Y
A
K
M
Y
L
D
G
Q
N
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788284
4699
524910
P4668
Y
A
D
A
I
P
E
P
V
S
T
E
I
T
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
P4724
K
A
E
I
S
K
P
P
I
P
A
R
P
K
K
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
E4450
Y
L
N
Q
R
G
S
E
L
S
L
E
N
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
98.1
94.6
N.A.
91.6
35.2
N.A.
N.A.
61.4
N.A.
69.4
N.A.
34.6
N.A.
31.1
41.4
Protein Similarity:
100
98.9
98.8
96.1
N.A.
96.2
51.7
N.A.
N.A.
75.5
N.A.
82.2
N.A.
51.9
N.A.
48.6
58.6
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
60
N.A.
80
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
N.A.
66.6
N.A.
100
N.A.
13.3
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
10
73
0
10
0
0
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
55
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
10
10
0
0
0
19
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
10
55
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
0
10
10
0
0
0
10
0
0
0
10
0
0
% I
% Lys:
10
0
0
0
0
73
0
0
10
0
0
0
0
19
19
% K
% Leu:
0
10
10
0
0
0
55
0
19
0
10
10
0
0
0
% L
% Met:
0
0
10
0
0
0
10
0
55
0
0
0
0
0
0
% M
% Asn:
64
0
10
0
0
0
0
0
0
0
10
0
64
0
0
% N
% Pro:
10
64
0
10
0
10
10
19
0
10
0
0
10
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
55
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
64
% R
% Ser:
0
10
0
0
10
0
10
10
0
19
0
0
10
10
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
10
0
10
10
0
% T
% Val:
0
0
55
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
0
64
0
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _