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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP1B
All Species:
14.24
Human Site:
Y4150
Identified Species:
31.33
UniProt:
Q9NZR2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZR2
NP_061027.2
4599
515498
Y4150
F
G
H
G
S
V
E
Y
L
A
L
N
I
D
K
Chimpanzee
Pan troglodytes
XP_515817
4636
518955
Y4187
F
G
H
G
S
V
E
Y
L
A
L
N
I
D
K
Rhesus Macaque
Macaca mulatta
XP_001117994
4592
514768
Y4143
F
G
H
G
S
V
E
Y
L
A
L
N
I
D
K
Dog
Lupus familis
XP_533343
4492
503712
Y4043
F
G
H
G
S
V
E
Y
L
A
L
D
I
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI18
4599
513616
V4150
F
G
H
G
S
V
E
V
L
A
L
G
V
D
K
Rat
Rattus norvegicus
P98158
4660
519258
D4250
D
D
R
V
Y
W
S
D
S
K
E
D
V
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
S4121
I
H
K
F
G
H
K
S
V
T
N
L
T
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920039
4500
501034
P4082
Y
G
K
R
P
I
E
P
L
D
L
G
I
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788284
4699
524910
P4271
A
L
P
G
S
Q
E
P
P
P
L
K
C
T
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
I4325
D
G
R
Y
L
K
K
I
V
A
G
H
L
Q
Q
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
R4061
F
G
N
Q
S
T
D
R
K
S
L
T
Y
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
98.1
94.6
N.A.
91.6
35.2
N.A.
N.A.
61.4
N.A.
69.4
N.A.
34.6
N.A.
31.1
41.4
Protein Similarity:
100
98.9
98.8
96.1
N.A.
96.2
51.7
N.A.
N.A.
75.5
N.A.
82.2
N.A.
51.9
N.A.
48.6
58.6
P-Site Identity:
100
100
100
93.3
N.A.
80
0
N.A.
N.A.
0
N.A.
40
N.A.
26.6
N.A.
13.3
26.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
20
N.A.
N.A.
13.3
N.A.
60
N.A.
26.6
N.A.
46.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% C
% Asp:
19
10
0
0
0
0
10
10
0
10
0
19
0
46
0
% D
% Glu:
0
0
0
0
0
0
64
0
0
0
10
0
0
10
10
% E
% Phe:
55
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
73
0
55
10
0
0
0
0
0
10
19
0
0
10
% G
% His:
0
10
46
0
0
10
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
10
0
0
0
0
46
10
0
% I
% Lys:
0
0
19
0
0
10
19
0
10
10
0
10
0
0
55
% K
% Leu:
0
10
0
0
10
0
0
0
55
0
73
10
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
10
28
0
0
0
% N
% Pro:
0
0
10
0
10
0
0
19
10
10
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
10
0
0
0
0
0
0
0
10
10
% Q
% Arg:
0
0
19
10
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
64
0
10
10
10
10
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
10
0
10
10
10
10
% T
% Val:
0
0
0
10
0
46
0
10
19
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
10
0
0
37
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _