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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CISD1
All Species:
34.85
Human Site:
Y71
Identified Species:
63.89
UniProt:
Q9NZ45
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZ45
NP_060934.1
108
12199
Y71
D
L
G
D
K
A
V
Y
C
R
C
W
R
S
K
Chimpanzee
Pan troglodytes
XP_001160242
111
12709
Y74
D
L
G
D
K
A
V
Y
C
R
C
W
R
S
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536355
106
12082
Y69
D
L
G
D
K
A
V
Y
C
R
C
W
R
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91WS0
108
12078
Y71
D
L
G
D
K
A
V
Y
C
R
C
W
R
S
K
Rat
Rattus norvegicus
B0K020
108
12078
Y71
D
L
G
D
K
A
V
Y
C
R
C
W
R
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507749
114
12779
Y77
D
L
G
D
K
A
V
Y
C
R
C
W
R
S
K
Chicken
Gallus gallus
XP_421526
108
11845
Y71
D
L
G
D
K
A
V
Y
C
R
C
W
R
S
K
Frog
Xenopus laevis
Q6PCF8
135
15348
Y98
L
H
L
A
K
A
A
Y
C
R
C
W
R
S
K
Zebra Danio
Brachydanio rerio
NP_956899
107
11815
Y70
D
L
G
D
K
A
V
Y
C
R
C
W
R
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VAM6
133
14614
I88
E
P
K
V
V
D
M
I
D
V
E
D
I
A
E
Honey Bee
Apis mellifera
XP_394113
130
14413
F93
D
I
T
E
K
A
A
F
C
R
C
W
R
S
K
Nematode Worm
Caenorhab. elegans
NP_001022387
103
11262
F66
D
I
G
E
K
K
A
F
C
R
C
W
K
S
E
Sea Urchin
Strong. purpuratus
XP_791538
105
11358
F66
D
L
G
D
K
E
A
F
C
R
C
W
R
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.8
N.A.
92.5
N.A.
86.1
86.1
N.A.
77.1
77.7
45.9
67.5
N.A.
36.8
37.6
48.1
40.7
Protein Similarity:
100
93.6
N.A.
98.1
N.A.
94.4
91.6
N.A.
85.9
88.8
61.4
78.6
N.A.
57.8
56.9
63.8
58.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
66.6
100
N.A.
0
66.6
53.3
80
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
66.6
100
N.A.
26.6
86.6
86.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
77
31
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
93
0
93
0
0
0
0
% C
% Asp:
85
0
0
70
0
8
0
0
8
0
0
8
0
0
0
% D
% Glu:
8
0
0
16
0
8
0
0
0
0
8
0
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% F
% Gly:
0
0
77
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
0
0
8
0
93
8
0
0
0
0
0
0
8
0
85
% K
% Leu:
8
70
8
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
93
0
0
85
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
93
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
62
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _