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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CISD1
All Species:
1.52
Human Site:
S6
Identified Species:
2.78
UniProt:
Q9NZ45
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZ45
NP_060934.1
108
12199
S6
_
_
M
S
L
T
S
S
S
S
V
R
V
E
W
Chimpanzee
Pan troglodytes
XP_001160242
111
12709
I9
Q
N
F
L
L
S
S
I
A
W
S
W
V
E
W
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536355
106
12082
A22
V
T
I
A
A
G
T
A
A
I
G
Y
L
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q91WS0
108
12078
N6
_
_
M
G
L
S
S
N
S
A
V
R
V
E
W
Rat
Rattus norvegicus
B0K020
108
12078
D6
_
_
M
G
L
S
S
D
S
P
V
R
V
E
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507749
114
12779
Q12
T
W
Y
V
N
A
V
Q
R
G
G
S
V
E
W
Chicken
Gallus gallus
XP_421526
108
11845
N6
_
_
M
G
L
G
Q
N
G
A
V
R
V
E
W
Frog
Xenopus laevis
Q6PCF8
135
15348
I31
P
D
S
I
A
G
F
I
R
L
T
V
S
E
W
Zebra Danio
Brachydanio rerio
NP_956899
107
11815
A23
V
S
V
T
F
G
A
A
A
V
G
L
L
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VAM6
133
14614
P42
D
W
L
A
L
I
P
P
T
V
V
V
A
G
L
Honey Bee
Apis mellifera
XP_394113
130
14413
F28
P
D
S
I
G
G
W
F
R
L
G
I
R
D
W
Nematode Worm
Caenorhab. elegans
NP_001022387
103
11262
T14
V
S
G
R
C
V
A
T
T
A
A
V
L
A
G
Sea Urchin
Strong. purpuratus
XP_791538
105
11358
A6
_
_
M
V
M
E
G
A
D
W
L
R
M
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.8
N.A.
92.5
N.A.
86.1
86.1
N.A.
77.1
77.7
45.9
67.5
N.A.
36.8
37.6
48.1
40.7
Protein Similarity:
100
93.6
N.A.
98.1
N.A.
94.4
91.6
N.A.
85.9
88.8
61.4
78.6
N.A.
57.8
56.9
63.8
58.3
P-Site Identity:
100
33.3
N.A.
0
N.A.
69.2
69.2
N.A.
20
53.8
13.3
0
N.A.
13.3
6.6
0
15.3
P-Site Similarity:
100
46.6
N.A.
46.6
N.A.
92.3
76.9
N.A.
20
69.2
13.3
46.6
N.A.
33.3
13.3
33.3
46.1
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
16
8
16
24
24
24
8
0
8
16
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
0
0
0
0
0
8
8
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
0
54
0
% E
% Phe:
0
0
8
0
8
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
24
8
39
8
0
8
8
31
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
16
0
8
0
16
0
8
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
8
47
0
0
0
0
16
8
8
24
0
8
% L
% Met:
0
0
39
0
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
8
0
0
16
0
0
0
0
0
0
0
% N
% Pro:
16
0
0
0
0
0
8
8
0
8
0
0
0
0
8
% P
% Gln:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
24
0
0
39
8
0
0
% R
% Ser:
0
16
16
8
0
24
31
8
24
8
8
8
8
0
0
% S
% Thr:
8
8
0
8
0
8
8
8
16
0
8
0
0
0
0
% T
% Val:
24
0
8
16
0
8
8
0
0
16
39
24
47
16
0
% V
% Trp:
0
16
0
0
0
0
8
0
0
16
0
8
0
0
62
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
16
% Y
% Spaces:
39
39
0
0
0
0
0
0
0
0
0
0
0
0
0
% _