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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK2
All Species:
5.76
Human Site:
Y108
Identified Species:
12.67
UniProt:
Q9NYY3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYY3
NP_006613.2
685
78237
Y108
D
L
T
N
N
K
V
Y
A
A
K
I
I
P
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102530
669
76425
Q107
S
R
V
A
K
P
H
Q
R
E
K
I
D
K
E
Dog
Lupus familis
XP_535242
686
78191
Y109
D
L
T
N
N
K
V
Y
A
A
K
I
I
P
H
Cat
Felis silvestris
Mouse
Mus musculus
P53351
682
77794
K108
N
N
K
V
Y
A
A
K
I
I
P
H
S
R
V
Rat
Rattus norvegicus
Q9R012
682
77902
K108
N
N
K
V
Y
A
A
K
I
I
P
H
S
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424739
671
76488
Q111
S
R
V
A
K
P
H
Q
R
E
K
I
D
K
E
Frog
Xenopus laevis
P70032
598
68193
T90
P
H
Q
K
D
K
M
T
M
E
I
A
I
Q
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
E68
M
I
K
H
N
Q
K
E
K
T
A
Q
E
I
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34331
649
73615
D108
K
L
F
N
F
F
E
D
N
L
N
V
Y
I
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
E107
E
H
V
F
E
D
Q
E
N
V
Y
I
L
L
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
A108
D
D
S
G
E
I
F
A
A
K
T
V
A
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
97.6
N.A.
96.7
97
N.A.
N.A.
86.7
37.5
N.A.
N.A.
33.2
N.A.
27
N.A.
Protein Similarity:
100
N.A.
97.3
98.2
N.A.
97.5
97.8
N.A.
N.A.
91.2
57.3
N.A.
N.A.
54.8
N.A.
44.9
N.A.
P-Site Identity:
100
N.A.
13.3
100
N.A.
0
0
N.A.
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
13.3
100
N.A.
6.6
6.6
N.A.
N.A.
13.3
26.6
N.A.
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
31
N.A.
N.A.
31.7
N.A.
Protein Similarity:
N.A.
50.6
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
19
19
10
28
19
10
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
28
10
0
0
10
10
0
10
0
0
0
0
19
0
0
% D
% Glu:
10
0
0
0
19
0
10
19
0
28
0
0
10
0
28
% E
% Phe:
0
0
10
10
10
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
19
0
10
0
0
19
0
0
0
0
19
0
0
19
% H
% Ile:
0
10
0
0
0
10
0
0
19
19
10
46
28
19
0
% I
% Lys:
10
0
28
10
19
28
10
19
10
10
37
0
0
28
0
% K
% Leu:
0
28
0
0
0
0
0
0
0
10
0
0
10
10
0
% L
% Met:
10
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% M
% Asn:
19
19
0
28
28
0
0
0
19
0
10
0
0
0
0
% N
% Pro:
10
0
0
0
0
19
0
0
0
0
19
0
0
19
0
% P
% Gln:
0
0
10
0
0
10
10
19
0
0
0
10
0
10
0
% Q
% Arg:
0
19
0
0
0
0
0
0
19
0
0
0
0
19
10
% R
% Ser:
19
0
10
0
0
0
0
0
0
0
0
0
19
0
0
% S
% Thr:
0
0
19
0
0
0
0
10
0
10
10
0
0
0
19
% T
% Val:
0
0
28
19
0
0
19
0
0
10
0
19
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
19
0
0
19
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _