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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK2
All Species:
19.7
Human Site:
T384
Identified Species:
43.33
UniProt:
Q9NYY3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYY3
NP_006613.2
685
78237
T384
D
K
A
R
Y
I
D
T
H
N
R
V
S
K
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102530
669
76425
T368
D
K
A
R
Y
I
D
T
H
N
R
V
S
K
E
Dog
Lupus familis
XP_535242
686
78191
T385
D
K
A
R
Y
I
D
T
H
N
R
V
S
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P53351
682
77794
T381
D
K
A
R
Y
N
D
T
H
N
K
V
S
K
E
Rat
Rattus norvegicus
Q9R012
682
77902
T381
D
K
A
R
Y
N
D
T
H
N
K
V
S
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424739
671
76488
N372
D
K
A
R
Y
F
D
N
H
N
R
L
A
K
E
Frog
Xenopus laevis
P70032
598
68193
P314
T
T
C
L
T
V
P
P
R
F
S
I
A
P
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
T292
F
L
P
S
S
C
L
T
M
A
P
R
I
G
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34331
649
73615
N352
P
Q
H
I
V
S
N
N
A
D
R
E
R
A
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
P331
S
V
K
V
P
S
Q
P
A
P
K
S
A
E
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
S395
R
Q
K
R
D
Y
I
S
S
I
K
S
S
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
97.6
N.A.
96.7
97
N.A.
N.A.
86.7
37.5
N.A.
N.A.
33.2
N.A.
27
N.A.
Protein Similarity:
100
N.A.
97.3
98.2
N.A.
97.5
97.8
N.A.
N.A.
91.2
57.3
N.A.
N.A.
54.8
N.A.
44.9
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
N.A.
73.3
0
N.A.
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
20
N.A.
N.A.
6.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
31
N.A.
N.A.
31.7
N.A.
Protein Similarity:
N.A.
50.6
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
55
0
0
0
0
0
19
10
0
0
28
10
10
% A
% Cys:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
55
0
0
0
10
0
55
0
0
10
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
55
% E
% Phe:
10
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
10
0
0
0
0
0
55
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
28
10
0
0
10
0
10
10
10
0
% I
% Lys:
0
55
19
0
0
0
0
0
0
0
37
0
0
55
0
% K
% Leu:
0
10
0
10
0
0
10
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
19
10
19
0
55
0
0
0
0
0
% N
% Pro:
10
0
10
0
10
0
10
19
0
10
10
0
0
10
0
% P
% Gln:
0
19
0
0
0
0
10
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
0
64
0
0
0
0
10
0
46
10
10
0
0
% R
% Ser:
10
0
0
10
10
19
0
10
10
0
10
19
55
0
19
% S
% Thr:
10
10
0
0
10
0
0
55
0
0
0
0
0
0
0
% T
% Val:
0
10
0
10
10
10
0
0
0
0
0
46
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
55
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _