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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK2
All Species:
24.85
Human Site:
S301
Identified Species:
54.67
UniProt:
Q9NYY3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYY3
NP_006613.2
685
78237
S301
E
A
R
Y
T
M
P
S
S
L
L
A
P
A
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102530
669
76425
S285
E
A
R
Y
T
M
P
S
S
L
L
A
P
A
K
Dog
Lupus familis
XP_535242
686
78191
S302
E
A
R
Y
T
M
P
S
S
L
L
A
P
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P53351
682
77794
S298
E
A
R
Y
T
M
P
S
S
L
L
A
P
A
K
Rat
Rattus norvegicus
Q9R012
682
77902
S298
E
A
R
Y
T
M
P
S
S
L
L
A
P
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424739
671
76488
S289
E
A
R
Y
S
L
P
S
S
L
L
A
P
A
K
Frog
Xenopus laevis
P70032
598
68193
K239
M
Y
T
L
L
V
G
K
P
P
F
E
T
S
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
L217
G
C
V
M
Y
T
L
L
V
G
Q
P
P
F
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34331
649
73615
S257
H
N
N
Y
T
I
P
S
I
A
T
Q
P
A
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
D256
A
C
E
Y
S
F
P
D
H
V
S
V
S
D
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
R302
C
R
D
F
S
F
P
R
D
K
P
I
S
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
97.6
N.A.
96.7
97
N.A.
N.A.
86.7
37.5
N.A.
N.A.
33.2
N.A.
27
N.A.
Protein Similarity:
100
N.A.
97.3
98.2
N.A.
97.5
97.8
N.A.
N.A.
91.2
57.3
N.A.
N.A.
54.8
N.A.
44.9
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
0
N.A.
N.A.
6.6
N.A.
40
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
13.3
N.A.
N.A.
13.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
31
N.A.
N.A.
31.7
N.A.
Protein Similarity:
N.A.
50.6
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
55
0
0
0
0
0
0
0
10
0
55
0
64
10
% A
% Cys:
10
19
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
10
0
0
0
0
10
10
0
0
0
0
19
0
% D
% Glu:
55
0
10
0
0
0
0
0
0
0
0
10
0
0
19
% E
% Phe:
0
0
0
10
0
19
0
0
0
0
10
0
0
10
0
% F
% Gly:
10
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
10
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
55
% K
% Leu:
0
0
0
10
10
10
10
10
0
55
55
0
0
0
0
% L
% Met:
10
0
0
10
0
46
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
82
0
10
10
10
10
73
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% Q
% Arg:
0
10
55
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
28
0
0
64
55
0
10
0
19
10
0
% S
% Thr:
0
0
10
0
55
10
0
0
0
0
10
0
10
0
10
% T
% Val:
0
0
10
0
0
10
0
0
10
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
73
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _