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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK2
All Species:
25.15
Human Site:
S166
Identified Species:
55.33
UniProt:
Q9NYY3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYY3
NP_006613.2
685
78237
S166
L
E
Y
C
S
R
R
S
M
A
H
I
L
K
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102530
669
76425
S150
L
E
Y
C
S
R
R
S
M
A
H
I
L
K
A
Dog
Lupus familis
XP_535242
686
78191
S167
L
E
Y
C
S
R
R
S
M
A
H
I
L
K
A
Cat
Felis silvestris
Mouse
Mus musculus
P53351
682
77794
S163
L
E
Y
C
S
R
R
S
M
A
H
I
L
K
A
Rat
Rattus norvegicus
Q9R012
682
77902
S163
L
E
Y
C
S
R
R
S
M
A
H
I
L
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424739
671
76488
S154
L
E
Y
C
S
R
R
S
M
A
H
I
L
K
A
Frog
Xenopus laevis
P70032
598
68193
H133
R
R
S
L
L
E
L
H
K
R
R
K
A
V
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
M111
L
C
K
K
R
S
M
M
E
L
H
K
R
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34331
649
73615
L151
H
Q
I
V
D
G
V
L
Y
L
H
D
L
N
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
L150
L
I
C
G
L
K
Y
L
H
S
R
R
V
I
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
S165
L
E
I
C
P
N
G
S
L
M
E
L
L
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
97.6
N.A.
96.7
97
N.A.
N.A.
86.7
37.5
N.A.
N.A.
33.2
N.A.
27
N.A.
Protein Similarity:
100
N.A.
97.3
98.2
N.A.
97.5
97.8
N.A.
N.A.
91.2
57.3
N.A.
N.A.
54.8
N.A.
44.9
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
0
N.A.
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
0
N.A.
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
31
N.A.
N.A.
31.7
N.A.
Protein Similarity:
N.A.
50.6
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
55
0
0
10
0
55
% A
% Cys:
0
10
10
64
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
64
0
0
0
10
0
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
10
10
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
10
10
0
73
0
0
0
10
% H
% Ile:
0
10
19
0
0
0
0
0
0
0
0
55
0
10
10
% I
% Lys:
0
0
10
10
0
10
0
0
10
0
0
19
0
64
10
% K
% Leu:
82
0
0
10
19
0
10
19
10
19
0
10
73
0
0
% L
% Met:
0
0
0
0
0
0
10
10
55
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
10
55
55
0
0
10
19
10
10
10
10
% R
% Ser:
0
0
10
0
55
10
0
64
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
10
0
0
10
0
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
55
0
0
0
10
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _