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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASL12
All Species:
29.7
Human Site:
T258
Identified Species:
50.26
UniProt:
Q9NYN1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYN1
NP_057647.1
266
29662
T258
K
R
K
A
P
T
L
T
L
L
K
G
F
K
I
Chimpanzee
Pan troglodytes
XP_510479
266
29602
T258
K
R
K
A
P
T
L
T
L
L
K
G
F
K
I
Rhesus Macaque
Macaca mulatta
XP_001108511
266
29588
T258
K
R
K
A
P
T
L
T
L
L
K
G
F
K
I
Dog
Lupus familis
XP_544725
234
26404
L227
R
K
A
P
T
L
T
L
L
K
G
F
K
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q08AT1
266
29536
T258
K
R
K
A
P
T
L
T
L
L
K
G
F
K
I
Rat
Rattus norvegicus
Q5BJQ5
217
24743
K210
K
K
I
K
A
S
L
K
K
K
R
E
N
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518218
343
37266
T335
K
R
K
A
P
A
L
T
L
L
K
G
F
K
I
Chicken
Gallus gallus
XP_413899
265
29618
T257
K
R
K
A
P
T
L
T
L
L
K
G
F
K
I
Frog
Xenopus laevis
Q8AVS6
248
27595
S240
R
F
K
Q
A
L
S
S
K
V
R
T
A
T
S
Zebra Danio
Brachydanio rerio
Q7SZ59
255
28392
T247
K
R
R
A
P
T
L
T
L
L
K
G
F
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
K177
E
K
K
Q
K
K
P
K
K
S
L
C
V
L
L
Honey Bee
Apis mellifera
XP_001119889
216
24087
S209
R
A
Y
S
R
G
K
S
D
S
A
L
P
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789332
282
32318
K271
K
R
T
V
S
S
F
K
F
F
N
K
G
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P22126
213
24008
C206
D
E
D
V
Q
A
G
C
C
A
K
C
I
M
M
Conservation
Percent
Protein Identity:
100
99.2
98.1
82.7
N.A.
93.6
30.8
N.A.
46.9
74
27.8
63.9
N.A.
24.8
33
N.A.
37.5
Protein Similarity:
100
100
99.2
84.9
N.A.
95.1
48.5
N.A.
57.1
84.9
46.9
77
N.A.
40.5
47.3
N.A.
54.9
P-Site Identity:
100
100
100
6.6
N.A.
100
20
N.A.
93.3
100
6.6
93.3
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
100
40
N.A.
93.3
100
33.3
100
N.A.
26.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
50
15
15
0
0
0
8
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
15
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
8
% D
% Glu:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
8
0
0
0
0
8
0
8
8
0
8
50
8
8
% F
% Gly:
0
0
0
0
0
8
8
0
0
0
8
50
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
58
% I
% Lys:
65
22
58
8
8
8
8
22
22
15
58
8
8
58
8
% K
% Leu:
0
0
0
0
0
15
58
8
58
50
8
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
8
50
0
8
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
15
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
22
58
8
0
8
0
0
0
0
0
15
0
0
0
0
% R
% Ser:
0
0
0
8
8
15
8
15
0
15
0
0
0
0
8
% S
% Thr:
0
0
8
0
8
43
8
50
0
0
0
8
0
8
0
% T
% Val:
0
0
0
15
0
0
0
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _