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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASL12
All Species:
25.15
Human Site:
T145
Identified Species:
42.56
UniProt:
Q9NYN1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYN1
NP_057647.1
266
29662
T145
M
A
Q
Y
R
Q
V
T
K
A
E
G
V
A
L
Chimpanzee
Pan troglodytes
XP_510479
266
29602
T145
M
A
Q
Y
R
Q
V
T
K
A
E
G
V
A
L
Rhesus Macaque
Macaca mulatta
XP_001108511
266
29588
T145
M
A
Q
Y
R
Q
V
T
K
A
E
G
V
A
L
Dog
Lupus familis
XP_544725
234
26404
F129
G
K
F
G
C
L
F
F
E
V
S
A
C
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q08AT1
266
29536
T145
M
A
Q
Y
R
Q
V
T
K
A
E
G
A
A
L
Rat
Rattus norvegicus
Q5BJQ5
217
24743
K112
Q
S
F
Q
E
A
A
K
F
K
E
L
I
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518218
343
37266
V150
D
L
E
Q
Y
S
S
V
V
L
G
L
T
Y
W
Chicken
Gallus gallus
XP_413899
265
29618
T147
M
E
Q
Y
R
Q
V
T
K
A
E
G
M
S
L
Frog
Xenopus laevis
Q8AVS6
248
27595
P142
R
H
A
R
Q
L
H
P
D
N
R
I
P
I
V
Zebra Danio
Brachydanio rerio
Q7SZ59
255
28392
S148
M
E
R
Y
R
Q
V
S
K
A
D
G
A
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
V79
M
K
N
G
Q
G
F
V
L
V
Y
S
I
T
A
Honey Bee
Apis mellifera
XP_001119889
216
24087
A111
S
F
N
F
V
R
K
A
K
E
T
L
A
V
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789332
282
32318
S173
M
E
R
Y
R
Q
V
S
K
L
D
G
S
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P22126
213
24008
V108
Y
Q
Q
Q
I
L
R
V
K
D
R
D
S
F
P
Conservation
Percent
Protein Identity:
100
99.2
98.1
82.7
N.A.
93.6
30.8
N.A.
46.9
74
27.8
63.9
N.A.
24.8
33
N.A.
37.5
Protein Similarity:
100
100
99.2
84.9
N.A.
95.1
48.5
N.A.
57.1
84.9
46.9
77
N.A.
40.5
47.3
N.A.
54.9
P-Site Identity:
100
100
100
0
N.A.
93.3
6.6
N.A.
0
80
0
66.6
N.A.
6.6
6.6
N.A.
60
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
20
N.A.
6.6
93.3
13.3
86.6
N.A.
20
26.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
29
8
0
0
8
8
8
0
43
0
8
22
43
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
8
15
8
0
0
8
% D
% Glu:
0
22
8
0
8
0
0
0
8
8
43
0
0
0
0
% E
% Phe:
0
8
15
8
0
0
15
8
8
0
0
0
0
15
0
% F
% Gly:
8
0
0
15
0
8
0
0
0
0
8
50
0
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
8
15
8
0
% I
% Lys:
0
15
0
0
0
0
8
8
65
8
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
22
0
0
8
15
0
22
0
8
50
% L
% Met:
58
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
15
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% P
% Gln:
8
8
43
22
15
50
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
0
15
8
50
8
8
0
0
0
15
0
0
0
0
% R
% Ser:
8
8
0
0
0
8
8
15
0
0
8
8
15
8
0
% S
% Thr:
0
0
0
0
0
0
0
36
0
0
8
0
8
8
0
% T
% Val:
0
0
0
0
8
0
50
22
8
15
0
0
22
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
50
8
0
0
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _