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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASL12
All Species:
12.73
Human Site:
S109
Identified Species:
21.54
UniProt:
Q9NYN1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYN1
NP_057647.1
266
29662
S109
S
R
Q
S
F
D
S
S
S
S
Y
L
E
L
L
Chimpanzee
Pan troglodytes
XP_510479
266
29602
S109
S
R
Q
S
F
D
S
S
S
S
Y
L
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001108511
266
29588
S109
S
R
Q
S
F
D
S
S
G
S
Y
L
E
L
L
Dog
Lupus familis
XP_544725
234
26404
R93
L
H
A
K
E
T
Q
R
S
S
P
A
L
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q08AT1
266
29536
S109
S
R
A
S
F
E
G
S
S
S
Y
L
E
L
L
Rat
Rattus norvegicus
Q5BJQ5
217
24743
A76
Y
L
D
I
L
D
T
A
G
Q
A
E
F
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518218
343
37266
C114
D
K
G
S
F
E
G
C
R
G
Y
L
D
I
I
Chicken
Gallus gallus
XP_413899
265
29618
C111
D
R
R
S
F
E
G
C
G
R
Y
L
D
I
L
Frog
Xenopus laevis
Q8AVS6
248
27595
N106
L
E
S
N
E
Q
L
N
K
S
L
R
W
A
D
Zebra Danio
Brachydanio rerio
Q7SZ59
255
28392
C112
N
R
S
S
F
E
V
C
Q
Q
Y
L
E
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
Q43
I
E
D
S
Y
R
K
Q
V
E
V
D
G
Q
Q
Honey Bee
Apis mellifera
XP_001119889
216
24087
P75
F
E
I
L
D
T
C
P
K
S
E
D
E
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789332
282
32318
K137
K
Q
S
F
S
Q
A
K
E
L
L
Q
E
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P22126
213
24008
M72
G
Q
E
E
Y
S
A
M
R
E
Q
Y
M
R
T
Conservation
Percent
Protein Identity:
100
99.2
98.1
82.7
N.A.
93.6
30.8
N.A.
46.9
74
27.8
63.9
N.A.
24.8
33
N.A.
37.5
Protein Similarity:
100
100
99.2
84.9
N.A.
95.1
48.5
N.A.
57.1
84.9
46.9
77
N.A.
40.5
47.3
N.A.
54.9
P-Site Identity:
100
100
93.3
26.6
N.A.
80
6.6
N.A.
26.6
40
6.6
40
N.A.
6.6
20
N.A.
13.3
P-Site Similarity:
100
100
93.3
26.6
N.A.
86.6
20
N.A.
60
66.6
20
60
N.A.
13.3
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
0
15
8
0
0
8
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
8
22
0
0
0
0
0
0
0
% C
% Asp:
15
0
15
0
8
29
0
0
0
0
0
15
15
0
8
% D
% Glu:
0
22
8
8
15
29
0
0
8
15
8
8
50
0
0
% E
% Phe:
8
0
0
8
50
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
8
0
0
0
22
0
22
8
0
0
8
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
0
0
0
0
0
0
0
0
0
15
8
% I
% Lys:
8
8
0
8
0
0
8
8
15
0
0
0
0
0
0
% K
% Leu:
15
8
0
8
8
0
8
0
0
8
15
50
8
50
43
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% P
% Gln:
0
15
22
0
0
15
8
8
8
15
8
8
0
8
8
% Q
% Arg:
0
43
8
0
0
8
0
8
15
8
0
8
0
8
0
% R
% Ser:
29
0
22
58
8
8
22
29
29
50
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
15
8
0
0
0
0
0
0
15
8
% T
% Val:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
0
0
0
15
0
0
0
0
0
50
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _