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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP39A1
All Species:
20.3
Human Site:
Y197
Identified Species:
40.61
UniProt:
Q9NYL5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYL5
NP_057677.2
469
54116
Y197
F
H
Q
Y
F
Q
V
Y
D
E
D
F
E
Y
G
Chimpanzee
Pan troglodytes
XP_518518
469
54055
Y197
F
H
Q
Y
F
Q
A
Y
D
E
D
F
E
Y
G
Rhesus Macaque
Macaca mulatta
XP_001102611
469
54028
Y197
F
H
Q
Y
F
Q
A
Y
D
E
D
F
E
Y
G
Dog
Lupus familis
XP_538946
469
54328
Y197
F
Y
Q
H
F
Q
A
Y
D
E
G
F
E
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKJ9
470
53556
Y200
F
Y
Q
Q
F
K
T
Y
D
E
G
F
E
Y
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511640
415
47952
W160
P
E
C
L
L
R
N
W
S
K
S
K
Q
W
F
Chicken
Gallus gallus
XP_420063
419
47287
L165
L
M
E
L
V
R
H
L
L
N
W
S
K
S
K
Frog
Xenopus laevis
NP_001083508
504
57241
P231
V
V
F
P
F
L
R
P
I
F
E
G
L
N
I
Zebra Danio
Brachydanio rerio
NP_001025360
464
52846
Y197
F
L
E
K
F
T
T
Y
D
E
G
F
E
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789944
362
41142
A115
Y
L
Q
L
L
L
D
A
Q
E
R
D
I
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LTL8
498
56791
F223
F
P
G
G
L
G
W
F
V
D
F
V
S
G
H
Baker's Yeast
Sacchar. cerevisiae
P10614
530
60702
T223
E
M
R
A
K
L
D
T
D
F
A
Y
L
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97
84.8
N.A.
74.8
N.A.
N.A.
62
49.2
21.2
49.2
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
99.5
97.8
92.3
N.A.
86.1
N.A.
N.A.
74.1
65
40.8
67.3
N.A.
N.A.
N.A.
N.A.
39.4
P-Site Identity:
100
93.3
93.3
73.3
N.A.
66.6
N.A.
N.A.
0
0
6.6
60
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
80
N.A.
N.A.
33.3
20
13.3
66.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.3
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
25
9
0
0
9
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
17
0
59
9
25
9
0
0
0
% D
% Glu:
9
9
17
0
0
0
0
0
0
59
9
0
50
0
0
% E
% Phe:
59
0
9
0
59
0
0
9
0
17
9
50
0
0
9
% F
% Gly:
0
0
9
9
0
9
0
0
0
0
25
9
0
9
59
% G
% His:
0
25
0
9
0
0
9
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
9
% I
% Lys:
0
0
0
9
9
9
0
0
0
9
0
9
9
0
9
% K
% Leu:
9
17
0
25
25
25
0
9
9
0
0
0
17
0
0
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
9
0
0
0
9
0
% N
% Pro:
9
9
0
9
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
50
9
0
34
0
0
9
0
0
0
9
0
0
% Q
% Arg:
0
0
9
0
0
17
9
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
9
0
9
9
9
9
9
% S
% Thr:
0
0
0
0
0
9
17
9
0
0
0
0
0
9
0
% T
% Val:
9
9
0
0
9
0
9
0
9
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
9
0
0
9
0
0
9
0
% W
% Tyr:
9
17
0
25
0
0
0
50
0
0
0
9
0
59
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _