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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPHK1
All Species:
20.91
Human Site:
Y184
Identified Species:
41.82
UniProt:
Q9NYA1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYA1
NP_001136073.1
384
42518
Y184
V
D
L
E
S
E
K
Y
R
R
L
G
E
M
R
Chimpanzee
Pan troglodytes
XP_001171292
616
65423
F314
V
D
I
Q
S
E
R
F
R
A
L
G
S
A
R
Rhesus Macaque
Macaca mulatta
XP_001099066
513
55416
Y270
V
D
L
E
S
E
K
Y
R
R
L
G
E
M
R
Dog
Lupus familis
XP_540448
477
51774
F274
V
D
L
E
S
E
K
F
R
R
L
G
E
M
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI15
382
42425
Y184
V
D
L
E
S
E
K
Y
R
R
L
G
E
I
R
Rat
Rattus norvegicus
Q91V26
383
42400
Y184
V
D
L
E
S
E
K
Y
R
S
L
G
E
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508019
326
34847
P153
A
Y
L
P
R
E
G
P
T
P
P
A
P
A
S
Chicken
Gallus gallus
XP_425374
361
38864
Y165
V
D
I
D
S
E
K
Y
R
R
L
G
N
A
R
Frog
Xenopus laevis
NP_001088560
509
55981
Y313
V
D
I
E
S
E
R
Y
R
F
M
G
S
A
R
Zebra Danio
Brachydanio rerio
XP_001922084
310
33789
F143
R
Q
I
G
A
L
R
F
I
L
G
T
L
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002317243
494
54399
A284
K
Y
R
W
M
G
S
A
R
L
D
F
Y
G
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001031689
485
53680
A288
K
F
R
W
M
G
S
A
R
F
D
I
Y
G
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29
64.3
72.5
N.A.
80.7
78.1
N.A.
51.5
50.2
40
44.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.2
67.2
75.6
N.A.
89.3
89
N.A.
61.2
63.5
51.6
58.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
100
93.3
N.A.
93.3
86.6
N.A.
13.3
73.3
60
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
100
N.A.
100
93.3
N.A.
13.3
86.6
80
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.4
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
39
N.A.
N.A.
36.4
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
0
0
17
0
9
0
9
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
9
0
0
0
0
0
0
17
0
0
0
0
% D
% Glu:
0
0
0
50
0
75
0
0
0
0
0
0
42
0
0
% E
% Phe:
0
9
0
0
0
0
0
25
0
17
0
9
0
0
0
% F
% Gly:
0
0
0
9
0
17
9
0
0
0
9
67
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
34
0
0
0
0
0
9
0
0
9
0
17
0
% I
% Lys:
17
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
50
0
0
9
0
0
0
17
59
0
9
0
17
% L
% Met:
0
0
0
0
17
0
0
0
0
0
9
0
0
25
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
9
0
0
0
9
0
9
9
0
9
0
0
% P
% Gln:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
17
0
9
0
25
0
84
42
0
0
0
0
75
% R
% Ser:
0
0
0
0
67
0
17
0
0
9
0
0
17
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% T
% Val:
67
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
50
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _