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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX56
All Species:
28.79
Human Site:
S223
Identified Species:
48.72
UniProt:
Q9NY93
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NY93
NP_061955.1
547
61590
S223
V
T
L
K
L
Q
E
S
Q
L
P
G
P
D
Q
Chimpanzee
Pan troglodytes
XP_001145021
547
61601
S223
V
T
L
K
L
Q
E
S
Q
L
P
G
P
D
Q
Rhesus Macaque
Macaca mulatta
XP_001090331
546
61504
S223
V
T
L
K
L
Q
E
S
Q
L
P
G
P
D
Q
Dog
Lupus familis
XP_850575
570
63900
S248
V
T
L
K
L
Q
E
S
Q
L
P
G
P
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0R4
546
61194
S223
V
T
L
K
L
Q
E
S
Q
L
P
G
P
D
Q
Rat
Rattus norvegicus
NP_001004211
482
54434
A197
L
S
L
I
R
G
K
A
L
L
F
V
N
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084622
552
62481
S218
V
T
L
K
L
E
E
S
Q
L
P
D
S
S
Q
Zebra Danio
Brachydanio rerio
NP_001003876
557
62952
S220
V
T
L
K
L
Q
G
S
Q
L
P
D
S
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523434
560
62865
P224
V
T
L
K
L
E
E
P
E
L
V
P
Q
D
Q
Honey Bee
Apis mellifera
XP_391920
547
62199
A226
V
I
L
K
L
E
E
A
P
L
A
P
L
S
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195983
520
58662
S220
I
T
L
K
L
A
E
S
Q
L
P
E
A
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SW44
626
69483
D264
I
V
L
T
L
T
E
D
N
D
K
E
E
A
V
Baker's Yeast
Sacchar. cerevisiae
Q06218
594
68041
E238
A
I
L
K
F
N
D
E
E
I
N
K
N
Q
N
Red Bread Mold
Neurospora crassa
Q7S6F3
676
76598
E310
T
M
L
D
L
K
E
E
F
S
N
E
D
E
K
Conservation
Percent
Protein Identity:
100
99.6
98.3
78
N.A.
90.8
79.8
N.A.
N.A.
N.A.
66.3
64.2
N.A.
47.1
50.8
N.A.
51.1
Protein Similarity:
100
99.8
99.2
84.5
N.A.
94.8
83.9
N.A.
N.A.
N.A.
80.9
80.2
N.A.
65.8
68.1
N.A.
69.6
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
N.A.
73.3
73.3
N.A.
60
46.6
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
N.A.
N.A.
80
73.3
N.A.
73.3
60
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.7
43.1
37.1
Protein Similarity:
N.A.
N.A.
N.A.
55.1
62.6
52.3
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
15
0
0
8
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
8
0
8
0
15
8
50
0
% D
% Glu:
0
0
0
0
0
22
79
15
15
0
0
22
8
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
8
0
0
0
0
36
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
15
0
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
79
0
8
8
0
0
0
8
8
0
0
8
% K
% Leu:
8
0
100
0
86
0
0
0
8
79
0
0
8
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
15
0
15
0
8
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
58
15
36
0
0
% P
% Gln:
0
0
0
0
0
43
0
0
58
0
0
0
8
8
65
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
0
0
0
0
0
58
0
8
0
0
15
22
0
% S
% Thr:
8
65
0
8
0
8
0
0
0
0
0
0
0
8
0
% T
% Val:
65
8
0
0
0
0
0
0
0
0
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _