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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA2D2
All Species:
21.82
Human Site:
Y274
Identified Species:
80
UniProt:
Q9NY47
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NY47
NP_001005505.1
1150
129876
Y274
A
P
K
K
I
D
L
Y
D
V
R
R
R
P
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090735
1453
162781
Y577
A
P
K
K
I
D
L
Y
D
V
R
R
R
P
W
Dog
Lupus familis
XP_852918
1147
129632
Y292
T
P
N
K
I
D
L
Y
D
V
R
R
R
P
W
Cat
Felis silvestris
Mouse
Mus musculus
Q6PHS9
1154
130366
Y277
A
P
K
K
I
D
L
Y
D
V
R
R
R
P
W
Rat
Rattus norvegicus
Q8CFG6
1157
130758
Y277
A
P
K
K
I
D
L
Y
D
V
R
R
R
P
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506420
1113
125732
Y259
S
P
N
K
I
D
L
Y
D
V
R
R
R
P
W
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013521
450
51704
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
78.5
52
N.A.
96.7
95.6
N.A.
51.9
N.A.
N.A.
29.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
78.7
68.9
N.A.
97.7
97.1
N.A.
68.6
N.A.
N.A.
34
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
100
100
N.A.
86.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
86.6
N.A.
100
100
N.A.
93.3
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
86
0
0
86
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
86
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
58
86
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
86
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
86
0
0
0
0
0
0
0
0
0
0
0
86
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
86
86
86
0
0
% R
% Ser:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
86
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
86
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _