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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL28 All Species: 20.61
Human Site: S368 Identified Species: 37.78
UniProt: Q9NXS3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXS3 NP_060128.2 571 64192 S368 P D T N T W T S L E R M N E S
Chimpanzee Pan troglodytes XP_001149345 684 76181 C477 D V A P T S T C R T S V G V A
Rhesus Macaque Macaca mulatta XP_001095031 571 64184 S368 P D T N T W T S L E R M N E S
Dog Lupus familis XP_547790 571 64226 S368 P D T N T W T S L E R M N E S
Cat Felis silvestris
Mouse Mus musculus Q9CR40 571 64107 S368 P D T N T W T S L E R M N E S
Rat Rattus norvegicus Q8K430 640 69714 R424 E V S M G T R R S C L G V A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513616 571 64248 S368 P D V N T W K S L E K M N E S
Chicken Gallus gallus Q5ZI33 586 66177 A377 T P R D S L A A C A A E G K I
Frog Xenopus laevis Q6NRH0 564 63190 N362 W Y S V A P M N V R R G L A G
Zebra Danio Brachydanio rerio Q5U374 564 62914 N362 W Y S V A T M N V R R G L A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 C406 D V A P T T S C R T S V G V A
Honey Bee Apis mellifera XP_397065 620 68991 C413 D V A P T T S C R T S V G V A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780225 597 66997 T394 P D I N T W S T V A S M H M C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.9 99.4 99.1 N.A. 97 38.4 N.A. 93.1 32.7 38.7 38.3 N.A. 40.1 40 N.A. 46.2
Protein Similarity: 100 53 99.4 99.6 N.A. 99.1 53.4 N.A. 96.6 50.5 56.7 57 N.A. 56.1 56.2 N.A. 65.1
P-Site Identity: 100 13.3 100 100 N.A. 100 0 N.A. 80 0 6.6 6.6 N.A. 6.6 6.6 N.A. 40
P-Site Similarity: 100 26.6 100 100 N.A. 100 13.3 N.A. 86.6 26.6 26.6 26.6 N.A. 26.6 26.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 24 0 16 0 8 8 0 16 8 0 0 24 31 % A
% Cys: 0 0 0 0 0 0 0 24 8 8 0 0 0 0 8 % C
% Asp: 24 47 0 8 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 39 0 8 0 39 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 0 24 31 0 16 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 8 0 0 8 0 % K
% Leu: 0 0 0 0 0 8 0 0 39 0 8 0 16 0 0 % L
% Met: 0 0 0 8 0 0 16 0 0 0 0 47 0 8 0 % M
% Asn: 0 0 0 47 0 0 0 16 0 0 0 0 39 0 0 % N
% Pro: 47 8 0 24 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 8 8 24 16 47 0 0 0 0 % R
% Ser: 0 0 24 0 8 8 24 39 8 0 31 0 0 0 39 % S
% Thr: 8 0 31 0 70 31 39 8 0 24 0 0 0 0 0 % T
% Val: 0 31 8 16 0 0 0 0 24 0 0 24 8 24 0 % V
% Trp: 16 0 0 0 0 47 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _