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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ING3 All Species: 27.58
Human Site: S319 Identified Species: 55.15
UniProt: Q9NXR8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXR8 NP_061944.2 418 46743 S319 Q S S S S S S S S S L S S C S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082715 370 41702 Y275 M A R E T V G Y S S S S A L M
Dog Lupus familis XP_532530 418 46766 S319 Q S S S S S S S S S L S S C S
Cat Felis silvestris
Mouse Mus musculus Q8VEK6 421 46828 S319 Q S S S S S S S S S S S S L S
Rat Rattus norvegicus Q498T3 421 46906 S319 Q S S S S S S S S S S S S L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509240 539 58659 S442 S S S S S S S S L S S C S S S
Chicken Gallus gallus Q5ZK36 417 46548 S319 S S S S S S S S S L S S C S S
Frog Xenopus laevis Q7ZX31 416 46165 L319 S S S S S S S L S S C S S S S
Zebra Danio Brachydanio rerio NP_957231 416 46555 S319 Q S S S S S S S S S L S S C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573316 686 70628 I376 G A A A S S A I A A A A S Q A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191966 285 31785 R190 S N S L V N S R E S S G N S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50947 330 37006 S234 R V A T T A V S P S T I S T A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 83.2 99 N.A. 95.4 96.6 N.A. 68.6 91.8 86.8 83.4 N.A. 33.6 N.A. N.A. 34.2
Protein Similarity: 100 N.A. 86.1 99 N.A. 96.1 97.1 N.A. 73 96.1 92.3 91.3 N.A. 44 N.A. N.A. 50.9
P-Site Identity: 100 N.A. 20 100 N.A. 86.6 86.6 N.A. 66.6 66.6 73.3 100 N.A. 20 N.A. N.A. 20
P-Site Similarity: 100 N.A. 40 100 N.A. 86.6 86.6 N.A. 66.6 66.6 73.3 100 N.A. 73.3 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 17 9 0 9 9 0 9 9 9 9 9 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 9 9 25 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 9 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 9 0 0 0 9 9 9 25 0 0 25 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 9 0 0 0 9 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % P
% Gln: 42 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % Q
% Arg: 9 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % R
% Ser: 34 67 75 67 75 75 75 67 67 84 50 67 75 34 67 % S
% Thr: 0 0 0 9 17 0 0 0 0 0 9 0 0 9 0 % T
% Val: 0 9 0 0 9 9 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _