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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM9 All Species: 13.33
Human Site: T946 Identified Species: 26.67
UniProt: Q9NXL9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXL9 NP_694987.1 1143 127338 T946 S H V S P G A T K I A V H S P
Chimpanzee Pan troglodytes XP_001163603 1143 127281 T946 S H V S P G A T K I A D H S P
Rhesus Macaque Macaca mulatta XP_001110306 1142 127490 T945 D H V S P G A T K I A V H S P
Dog Lupus familis XP_541221 1141 126374 K945 S S V I H A T K V A V P S A R
Cat Felis silvestris
Mouse Mus musculus Q2KHI9 1134 125796 T943 S K I P Q Q R T R R E A A V P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NRM6 1143 126576 D941 Q S K A E V E D P D T K A R L
Zebra Danio Brachydanio rerio XP_683173 660 73264 S487 A L A S P L L S R F D L V L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391969 625 70198 D452 D P L L S R F D L I L L L K D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785765 1217 134283 T959 N D S S M N S T S A L L V D G
Poplar Tree Populus trichocarpa XP_002325759 738 82610 D565 D T K N P E W D A V V S S H I
Maize Zea mays Q43704 768 85163 A595 L R D G S A N A K S G G G T L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FL33 776 86338 I603 A R T L E T I I R L A T A H A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 95.7 81.3 N.A. 74.7 N.A. N.A. N.A. N.A. 53.1 44.4 N.A. N.A. 26.4 N.A. 41.3
Protein Similarity: 100 98.9 97.3 87.6 N.A. 83.4 N.A. N.A. N.A. N.A. 65.4 50.5 N.A. N.A. 38.1 N.A. 57.9
P-Site Identity: 100 93.3 93.3 13.3 N.A. 20 N.A. N.A. N.A. N.A. 0 13.3 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 93.3 93.3 20 N.A. 33.3 N.A. N.A. N.A. N.A. 6.6 40 N.A. N.A. 20 N.A. 33.3
Percent
Protein Identity: 29.6 21.6 N.A. 21.9 N.A. N.A.
Protein Similarity: 41.9 37.9 N.A. 37.4 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 20 13.3 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 9 9 0 17 25 9 9 17 34 9 25 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 9 9 0 0 0 0 25 0 9 9 9 0 9 9 % D
% Glu: 0 0 0 0 17 9 9 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 25 0 0 0 0 9 9 9 0 9 % G
% His: 0 25 0 0 9 0 0 0 0 0 0 0 25 17 0 % H
% Ile: 0 0 9 9 0 0 9 9 0 34 0 0 0 0 9 % I
% Lys: 0 9 17 0 0 0 0 9 34 0 0 9 0 9 0 % K
% Leu: 9 9 9 17 0 9 9 0 9 9 17 25 9 9 17 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 9 0 9 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 0 9 42 0 0 0 9 0 0 9 0 0 34 % P
% Gln: 9 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 17 0 0 0 9 9 0 25 9 0 0 0 9 9 % R
% Ser: 34 17 9 42 17 0 9 9 9 9 0 9 17 25 0 % S
% Thr: 0 9 9 0 0 9 9 42 0 0 9 9 0 9 0 % T
% Val: 0 0 34 0 0 9 0 0 9 9 17 17 17 9 9 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _