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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNTLN All Species: 11.82
Human Site: T374 Identified Species: 43.33
UniProt: Q9NXG0 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NXG0 NP_001107867.1 1405 161615 T374 R N Q E D V H T A E S I S Y Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001102815 1338 154633 S328 I C F E T T K S N E A M L R Q
Dog Lupus familis XP_538669 1409 161458 T377 R N Q E D V H T A E S I S Y Q
Cat Felis silvestris
Mouse Mus musculus A2AM05 1397 160729 T374 R N Q E D V H T A E S M S Y Q
Rat Rattus norvegicus A9ZSY0 721 82702
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508142 1253 146140 S326 N L Q F T H S S L T H L E C L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781528 734 84563
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 85 73.1 N.A. 75.7 36.7 N.A. 56 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 22.2
Protein Similarity: 100 N.A. 87.8 80.6 N.A. 85.2 43.3 N.A. 69.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 35.3
P-Site Identity: 100 N.A. 20 100 N.A. 93.3 0 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 N.A. 40 100 N.A. 100 0 N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 43 0 15 0 0 0 0 % A
% Cys: 0 15 0 0 0 0 0 0 0 0 0 0 0 15 0 % C
% Asp: 0 0 0 0 43 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 58 0 0 0 0 0 58 0 0 15 0 0 % E
% Phe: 0 0 15 15 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 15 43 0 0 0 15 0 0 0 0 % H
% Ile: 15 0 0 0 0 0 0 0 0 0 0 29 0 0 0 % I
% Lys: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % K
% Leu: 0 15 0 0 0 0 0 0 15 0 0 15 15 0 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 29 0 0 0 % M
% Asn: 15 43 0 0 0 0 0 0 15 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 58 0 0 0 0 0 0 0 0 0 0 0 58 % Q
% Arg: 43 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % R
% Ser: 0 0 0 0 0 0 15 29 0 0 43 0 43 0 0 % S
% Thr: 0 0 0 0 29 15 0 43 0 15 0 0 0 0 0 % T
% Val: 0 0 0 0 0 43 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 43 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _