KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC49
All Species:
7.88
Human Site:
S295
Identified Species:
13.33
UniProt:
Q9NXE8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXE8
NP_060218.1
425
49647
S295
S
L
G
R
R
S
R
S
P
R
P
S
K
L
H
Chimpanzee
Pan troglodytes
XP_511442
425
49656
S295
S
L
G
R
R
S
R
S
P
R
P
S
K
L
H
Rhesus Macaque
Macaca mulatta
XP_001084106
361
42039
S254
T
G
Q
T
R
S
P
S
P
K
K
E
V
Y
Q
Dog
Lupus familis
XP_537657
420
49023
K295
S
R
S
P
R
P
S
K
P
H
N
S
K
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBF7
416
48793
P295
R
S
P
R
P
S
K
P
H
T
S
K
V
N
R
Rat
Rattus norvegicus
NP_001101765
415
48669
H295
S
P
R
P
S
K
Q
H
T
S
K
A
N
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509896
413
46346
P305
P
P
R
T
L
L
T
P
P
P
P
G
I
L
H
Chicken
Gallus gallus
Q5ZI03
460
53359
K338
R
E
K
Y
R
L
L
K
Q
D
S
S
A
E
N
Frog
Xenopus laevis
NP_001086504
387
45480
G270
S
K
G
S
K
T
G
G
S
Y
G
G
R
K
R
Zebra Danio
Brachydanio rerio
NP_998627
393
46591
P284
A
K
P
K
A
P
S
P
P
R
H
R
D
R
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608705
521
61859
K388
D
T
S
K
Q
R
E
K
R
R
S
R
T
P
E
Honey Bee
Apis mellifera
XP_624464
265
31449
L167
L
L
K
N
P
V
K
L
K
Q
L
R
Q
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201496
510
61353
D320
Q
R
R
D
C
S
D
D
G
S
E
D
E
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SI59
444
51384
S295
Q
G
R
S
R
S
R
S
G
S
P
G
G
R
S
Conservation
Percent
Protein Identity:
100
99.7
83.5
90.3
N.A.
88.9
88.9
N.A.
68.4
20
58.8
54.1
N.A.
33.4
28.4
N.A.
30
Protein Similarity:
100
100
84.2
94.1
N.A.
92.7
93.1
N.A.
77.1
34.3
73.6
70.1
N.A.
53.5
46.1
N.A.
50.7
P-Site Identity:
100
100
26.6
33.3
N.A.
13.3
6.6
N.A.
26.6
13.3
13.3
13.3
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
40
46.6
N.A.
20
20
N.A.
26.6
20
33.3
33.3
N.A.
20
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
48.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
8
8
0
8
0
8
8
0
0
% D
% Glu:
0
8
0
0
0
0
8
0
0
0
8
8
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
15
22
0
0
0
8
8
15
0
8
22
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
8
8
8
0
0
0
22
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
15
15
15
8
8
15
22
8
8
15
8
22
8
15
% K
% Leu:
8
22
0
0
8
15
8
8
0
0
8
0
0
29
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
8
0
8
8
15
% N
% Pro:
8
15
15
15
15
15
8
22
43
8
29
0
0
8
0
% P
% Gln:
15
0
8
0
8
0
8
0
8
8
0
0
8
0
8
% Q
% Arg:
15
15
29
22
43
8
22
0
8
29
0
22
8
29
22
% R
% Ser:
36
8
15
15
8
43
15
29
8
22
22
29
0
0
8
% S
% Thr:
8
8
0
15
0
8
8
0
8
8
0
0
8
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
15
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _