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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC49
All Species:
10.3
Human Site:
S275
Identified Species:
17.44
UniProt:
Q9NXE8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXE8
NP_060218.1
425
49647
S275
P
R
H
A
S
K
K
S
T
R
E
A
G
S
R
Chimpanzee
Pan troglodytes
XP_511442
425
49656
S275
P
R
H
A
S
K
K
S
T
R
E
A
G
S
R
Rhesus Macaque
Macaca mulatta
XP_001084106
361
42039
P234
R
R
S
W
S
P
R
P
S
K
P
H
N
S
K
Dog
Lupus familis
XP_537657
420
49023
S275
P
R
H
A
N
K
K
S
T
R
E
A
G
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBF7
416
48793
P275
K
S
T
K
E
E
R
P
R
D
R
R
S
R
S
Rat
Rattus norvegicus
NP_001101765
415
48669
R275
S
T
K
E
E
R
S
R
D
R
R
S
R
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509896
413
46346
T285
A
A
P
R
R
G
R
T
D
G
R
A
D
G
L
Chicken
Gallus gallus
Q5ZI03
460
53359
E318
T
R
K
E
K
L
Y
E
D
L
S
S
S
H
G
Frog
Xenopus laevis
NP_001086504
387
45480
D250
R
G
G
H
T
H
K
D
R
A
R
A
H
S
Q
Zebra Danio
Brachydanio rerio
NP_998627
393
46591
D264
S
P
L
S
H
K
A
D
R
D
N
H
S
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608705
521
61859
R368
A
R
R
Q
R
R
T
R
S
P
E
D
R
K
A
Honey Bee
Apis mellifera
XP_624464
265
31449
Y147
K
M
Q
E
D
P
L
Y
A
I
K
K
K
E
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201496
510
61353
R300
G
S
D
S
E
Q
D
R
R
R
D
S
R
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SI59
444
51384
D275
S
R
S
R
G
N
R
D
R
D
D
D
R
S
R
Conservation
Percent
Protein Identity:
100
99.7
83.5
90.3
N.A.
88.9
88.9
N.A.
68.4
20
58.8
54.1
N.A.
33.4
28.4
N.A.
30
Protein Similarity:
100
100
84.2
94.1
N.A.
92.7
93.1
N.A.
77.1
34.3
73.6
70.1
N.A.
53.5
46.1
N.A.
50.7
P-Site Identity:
100
100
20
93.3
N.A.
0
13.3
N.A.
6.6
6.6
20
20
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
46.6
100
N.A.
13.3
26.6
N.A.
20
13.3
33.3
26.6
N.A.
26.6
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
48.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
22
0
0
8
0
8
8
0
36
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
8
22
22
22
15
15
8
0
8
% D
% Glu:
0
0
0
22
22
8
0
8
0
0
29
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
8
8
0
0
0
8
0
0
22
8
8
% G
% His:
0
0
22
8
8
8
0
0
0
0
0
15
8
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
15
0
15
8
8
29
29
0
0
8
8
8
8
15
8
% K
% Leu:
0
0
8
0
0
8
8
0
0
8
0
0
0
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
8
0
0
0
0
8
0
8
0
0
% N
% Pro:
22
8
8
0
0
15
0
15
0
8
8
0
0
0
8
% P
% Gln:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
8
% Q
% Arg:
15
50
8
15
15
15
29
22
36
36
29
8
29
8
36
% R
% Ser:
22
15
15
15
22
0
8
22
15
0
8
22
22
58
8
% S
% Thr:
8
8
8
0
8
0
8
8
22
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _