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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC49
All Species:
16.97
Human Site:
S258
Identified Species:
28.72
UniProt:
Q9NXE8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXE8
NP_060218.1
425
49647
S258
G
H
G
M
K
N
H
S
R
S
R
S
S
S
H
Chimpanzee
Pan troglodytes
XP_511442
425
49656
S258
G
H
G
M
K
N
H
S
R
S
R
S
S
S
H
Rhesus Macaque
Macaca mulatta
XP_001084106
361
42039
S217
K
S
T
R
E
A
G
S
R
D
R
R
S
R
S
Dog
Lupus familis
XP_537657
420
49023
S258
M
H
G
L
R
N
H
S
R
S
R
S
S
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBF7
416
48793
S258
K
N
N
S
R
S
R
S
S
S
P
P
R
H
A
Rat
Rattus norvegicus
NP_001101765
415
48669
S258
K
N
H
S
R
S
S
S
S
P
A
R
H
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509896
413
46346
A268
S
Q
S
G
P
F
P
A
A
S
S
R
P
A
S
Chicken
Gallus gallus
Q5ZI03
460
53359
S301
K
G
K
F
S
E
A
S
S
S
D
S
E
G
K
Frog
Xenopus laevis
NP_001086504
387
45480
L233
H
R
E
S
G
Y
G
L
Q
V
R
D
H
G
Q
Zebra Danio
Brachydanio rerio
NP_998627
393
46591
T247
H
S
S
A
S
N
H
T
D
H
R
S
R
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608705
521
61859
R351
S
P
E
E
R
R
E
R
R
R
S
R
S
R
S
Honey Bee
Apis mellifera
XP_624464
265
31449
S130
P
P
S
L
R
F
F
S
G
N
E
Q
V
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201496
510
61353
R283
K
D
T
R
K
K
E
R
K
N
K
D
R
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SI59
444
51384
D258
Q
R
R
R
D
S
P
D
R
T
R
R
R
D
R
Conservation
Percent
Protein Identity:
100
99.7
83.5
90.3
N.A.
88.9
88.9
N.A.
68.4
20
58.8
54.1
N.A.
33.4
28.4
N.A.
30
Protein Similarity:
100
100
84.2
94.1
N.A.
92.7
93.1
N.A.
77.1
34.3
73.6
70.1
N.A.
53.5
46.1
N.A.
50.7
P-Site Identity:
100
100
26.6
80
N.A.
13.3
6.6
N.A.
6.6
20
6.6
26.6
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
33.3
93.3
N.A.
33.3
33.3
N.A.
20
20
13.3
33.3
N.A.
20
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
48.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
8
8
8
0
8
0
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
8
8
8
8
15
0
22
8
% D
% Glu:
0
0
15
8
8
8
15
0
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
8
0
15
8
0
0
0
0
0
0
0
0
% F
% Gly:
15
8
22
8
8
0
15
0
8
0
0
0
0
15
0
% G
% His:
15
22
8
0
0
0
29
0
0
8
0
0
15
8
22
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
36
0
8
0
22
8
0
0
8
0
8
0
0
0
8
% K
% Leu:
0
0
0
15
0
0
0
8
0
0
0
0
0
0
8
% L
% Met:
8
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
8
0
0
29
0
0
0
15
0
0
0
0
0
% N
% Pro:
8
15
0
0
8
0
15
0
0
8
8
8
8
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
8
0
0
8
0
0
8
% Q
% Arg:
0
15
8
22
36
8
8
15
43
8
50
36
29
22
15
% R
% Ser:
15
15
22
22
15
22
8
58
22
43
15
36
36
22
29
% S
% Thr:
0
0
15
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _