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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC49
All Species:
12.12
Human Site:
S206
Identified Species:
20.51
UniProt:
Q9NXE8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXE8
NP_060218.1
425
49647
S206
S
S
S
E
D
E
H
S
A
G
R
S
Q
K
K
Chimpanzee
Pan troglodytes
XP_511442
425
49656
S206
S
N
S
E
D
E
H
S
A
G
R
S
Q
K
K
Rhesus Macaque
Macaca mulatta
XP_001084106
361
42039
L165
S
K
V
P
G
Y
G
L
Q
V
R
N
S
D
R
Dog
Lupus familis
XP_537657
420
49023
G206
C
S
S
E
D
E
R
G
R
G
R
S
Q
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBF7
416
48793
S206
S
S
S
E
D
E
Q
S
Q
A
R
S
Q
K
K
Rat
Rattus norvegicus
NP_001101765
415
48669
S206
S
S
S
E
D
E
Q
S
H
G
R
S
Q
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509896
413
46346
G216
R
V
S
R
K
V
A
G
S
P
P
A
L
S
R
Chicken
Gallus gallus
Q5ZI03
460
53359
K249
K
Q
Q
K
K
K
G
K
S
K
H
K
K
H
K
Frog
Xenopus laevis
NP_001086504
387
45480
K181
K
S
K
K
K
K
K
K
E
K
K
K
R
R
K
Zebra Danio
Brachydanio rerio
NP_998627
393
46591
H195
E
K
R
K
D
K
E
H
R
R
R
S
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608705
521
61859
E299
D
E
S
S
D
E
E
E
E
P
R
R
K
H
K
Honey Bee
Apis mellifera
XP_624464
265
31449
P78
L
D
W
M
Y
K
G
P
N
H
L
V
N
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201496
510
61353
R231
R
D
R
R
K
E
S
R
R
S
K
D
R
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SI59
444
51384
D206
D
R
H
R
D
R
D
D
D
R
D
R
D
S
A
Conservation
Percent
Protein Identity:
100
99.7
83.5
90.3
N.A.
88.9
88.9
N.A.
68.4
20
58.8
54.1
N.A.
33.4
28.4
N.A.
30
Protein Similarity:
100
100
84.2
94.1
N.A.
92.7
93.1
N.A.
77.1
34.3
73.6
70.1
N.A.
53.5
46.1
N.A.
50.7
P-Site Identity:
100
93.3
13.3
73.3
N.A.
80
86.6
N.A.
6.6
6.6
13.3
20
N.A.
33.3
0
N.A.
6.6
P-Site Similarity:
100
100
26.6
73.3
N.A.
80
86.6
N.A.
26.6
33.3
46.6
33.3
N.A.
40
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
48.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
15
8
0
8
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
15
0
0
58
0
8
8
8
0
8
8
8
8
0
% D
% Glu:
8
8
0
36
0
50
15
8
15
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
22
15
0
29
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
15
8
8
8
8
0
0
15
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
15
15
8
22
29
29
8
15
0
15
15
15
15
36
58
% K
% Leu:
8
0
0
0
0
0
0
8
0
0
8
0
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
8
0
0
8
8
0
0
% N
% Pro:
0
0
0
8
0
0
0
8
0
15
8
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
15
0
15
0
0
0
36
0
0
% Q
% Arg:
15
8
15
22
0
8
8
8
22
15
58
15
15
22
15
% R
% Ser:
36
36
50
8
0
0
8
29
15
8
0
43
15
22
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
8
0
0
8
0
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _