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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKS1
All Species:
12.42
Human Site:
S269
Identified Species:
27.33
UniProt:
Q9NXB0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXB0
NP_060247.2
559
64528
S269
K
Y
T
I
D
N
V
S
P
H
A
Q
P
E
E
Chimpanzee
Pan troglodytes
XP_001172592
559
64593
S269
K
Y
T
I
D
N
V
S
P
H
A
Q
P
E
E
Rhesus Macaque
Macaca mulatta
XP_001103807
582
67318
S292
K
Y
T
I
D
N
V
S
P
L
A
Q
P
E
E
Dog
Lupus familis
XP_548230
625
71517
S335
K
Y
T
V
D
N
A
S
S
L
A
Q
P
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5SW45
561
64397
D269
S
A
W
K
Y
T
I
D
N
V
S
S
L
A
Q
Rat
Rattus norvegicus
Q499Q5
561
64504
D269
S
A
W
K
Y
T
I
D
N
V
S
S
L
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520585
416
47671
E137
I
T
W
E
P
S
E
E
F
I
R
N
N
H
V
Chicken
Gallus gallus
XP_415705
524
60060
R245
E
E
E
E
R
E
Q
R
V
F
R
D
L
F
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572804
699
80065
A369
E
N
V
T
P
L
E
A
Y
D
D
D
G
F
S
Honey Bee
Apis mellifera
XP_001120316
448
52853
M169
R
T
N
H
Y
L
Y
M
D
S
S
T
M
Y
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787637
523
59905
E244
M
D
S
E
P
K
E
E
D
E
C
T
L
C
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
91.4
81.7
N.A.
88.9
86.9
N.A.
60.2
67
N.A.
N.A.
N.A.
22.3
26.8
N.A.
42.2
Protein Similarity:
100
99.4
93.1
86.2
N.A.
95
94.4
N.A.
68.1
78.1
N.A.
N.A.
N.A.
36.4
42.4
N.A.
61.1
P-Site Identity:
100
100
93.3
73.3
N.A.
0
0
N.A.
0
0
N.A.
N.A.
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
93.3
80
N.A.
20
20
N.A.
6.6
6.6
N.A.
N.A.
N.A.
13.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
0
0
10
10
0
0
37
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% C
% Asp:
0
10
0
0
37
0
0
19
19
10
10
19
0
0
0
% D
% Glu:
19
10
10
28
0
10
28
19
0
10
0
0
0
37
37
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
0
0
19
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
19
0
0
0
10
0
% H
% Ile:
10
0
0
28
0
0
19
0
0
10
0
0
0
0
0
% I
% Lys:
37
0
0
19
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
19
0
0
0
19
0
0
37
0
0
% L
% Met:
10
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% M
% Asn:
0
10
10
0
0
37
0
0
19
0
0
10
10
0
0
% N
% Pro:
0
0
0
0
28
0
0
0
28
0
0
0
37
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
37
0
0
19
% Q
% Arg:
10
0
0
0
10
0
0
10
0
0
19
0
0
0
0
% R
% Ser:
19
0
10
0
0
10
0
37
10
10
28
19
0
0
10
% S
% Thr:
0
19
37
10
0
19
0
0
0
0
0
19
0
0
10
% T
% Val:
0
0
10
10
0
0
28
0
10
19
0
0
0
0
19
% V
% Trp:
0
0
28
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
37
0
0
28
0
10
0
10
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _