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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKS1
All Species:
22.42
Human Site:
S179
Identified Species:
49.33
UniProt:
Q9NXB0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXB0
NP_060247.2
559
64528
S179
M
E
G
G
I
L
K
S
R
I
V
T
W
E
P
Chimpanzee
Pan troglodytes
XP_001172592
559
64593
S179
M
E
G
S
I
L
K
S
R
I
V
T
W
E
P
Rhesus Macaque
Macaca mulatta
XP_001103807
582
67318
S202
M
E
G
G
I
L
K
S
R
L
V
T
W
E
P
Dog
Lupus familis
XP_548230
625
71517
S245
M
E
G
G
I
L
K
S
R
I
V
T
W
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5SW45
561
64397
S179
V
E
G
S
K
L
K
S
R
I
V
T
W
E
P
Rat
Rattus norvegicus
Q499Q5
561
64504
S179
V
E
G
S
K
L
K
S
R
I
I
T
W
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520585
416
47671
C47
L
Y
Q
N
E
A
A
C
Q
N
P
L
D
H
Q
Chicken
Gallus gallus
XP_415705
524
60060
K155
E
P
S
E
E
F
I
K
N
N
H
V
I
N
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572804
699
80065
T279
A
R
T
C
L
I
H
T
L
L
D
N
D
S
E
Honey Bee
Apis mellifera
XP_001120316
448
52853
N79
S
F
Y
K
N
E
T
N
C
L
T
E
S
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787637
523
59905
H154
T
D
Y
D
S
F
T
H
K
E
E
E
S
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
91.4
81.7
N.A.
88.9
86.9
N.A.
60.2
67
N.A.
N.A.
N.A.
22.3
26.8
N.A.
42.2
Protein Similarity:
100
99.4
93.1
86.2
N.A.
95
94.4
N.A.
68.1
78.1
N.A.
N.A.
N.A.
36.4
42.4
N.A.
61.1
P-Site Identity:
100
93.3
93.3
100
N.A.
80
73.3
N.A.
0
0
N.A.
N.A.
N.A.
0
0
N.A.
0
P-Site Similarity:
100
93.3
100
100
N.A.
86.6
86.6
N.A.
13.3
0
N.A.
N.A.
N.A.
26.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
10
10
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
0
0
0
10
0
19
0
0
% D
% Glu:
10
55
0
10
19
10
0
0
0
10
10
19
0
55
10
% E
% Phe:
0
10
0
0
0
19
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
55
28
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
10
0
0
10
0
% H
% Ile:
0
0
0
0
37
10
10
0
0
46
10
0
10
0
0
% I
% Lys:
0
0
0
10
19
0
55
10
10
0
0
0
0
0
10
% K
% Leu:
10
0
0
0
10
55
0
0
10
28
0
10
0
10
0
% L
% Met:
37
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
10
10
19
0
10
0
10
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
55
% P
% Gln:
0
0
10
0
0
0
0
0
10
0
0
0
0
10
10
% Q
% Arg:
0
10
0
0
0
0
0
0
55
0
0
0
0
0
0
% R
% Ser:
10
0
10
28
10
0
0
55
0
0
0
0
19
10
0
% S
% Thr:
10
0
10
0
0
0
19
10
0
0
10
55
0
0
19
% T
% Val:
19
0
0
0
0
0
0
0
0
0
46
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
55
0
0
% W
% Tyr:
0
10
19
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _