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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKS1
All Species:
22.73
Human Site:
S117
Identified Species:
50
UniProt:
Q9NXB0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXB0
NP_060247.2
559
64528
S117
E
I
L
K
L
E
N
S
G
G
K
K
N
R
R
Chimpanzee
Pan troglodytes
XP_001172592
559
64593
S117
E
I
L
K
L
E
N
S
G
G
K
K
N
R
R
Rhesus Macaque
Macaca mulatta
XP_001103807
582
67318
S140
E
I
L
K
L
E
N
S
G
G
K
K
N
R
R
Dog
Lupus familis
XP_548230
625
71517
S183
E
I
L
K
L
E
D
S
G
G
R
K
N
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5SW45
561
64397
S117
E
I
L
K
L
E
N
S
G
G
R
K
N
R
R
Rat
Rattus norvegicus
Q499Q5
561
64504
S117
E
V
L
K
L
E
N
S
G
G
R
K
N
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520585
416
47671
Chicken
Gallus gallus
XP_415705
524
60060
C104
F
T
N
L
E
E
H
C
Q
K
V
T
D
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572804
699
80065
L204
W
A
L
E
T
L
K
L
Q
Q
R
Y
L
R
K
Honey Bee
Apis mellifera
XP_001120316
448
52853
K28
S
N
F
K
I
R
V
K
I
V
Q
Q
R
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787637
523
59905
F103
F
D
W
Q
E
K
V
F
S
R
R
E
V
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
91.4
81.7
N.A.
88.9
86.9
N.A.
60.2
67
N.A.
N.A.
N.A.
22.3
26.8
N.A.
42.2
Protein Similarity:
100
99.4
93.1
86.2
N.A.
95
94.4
N.A.
68.1
78.1
N.A.
N.A.
N.A.
36.4
42.4
N.A.
61.1
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
0
6.6
N.A.
N.A.
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
20
N.A.
N.A.
N.A.
33.3
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
0
0
0
0
10
0
10
% D
% Glu:
55
0
0
10
19
64
0
0
0
0
0
10
0
0
0
% E
% Phe:
19
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
55
55
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
46
0
0
10
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
64
0
10
10
10
0
10
28
55
0
0
10
% K
% Leu:
0
0
64
10
55
10
0
10
0
0
0
0
10
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
46
0
0
0
0
0
55
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
19
10
10
10
0
10
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
10
46
0
10
64
55
% R
% Ser:
10
0
0
0
0
0
0
55
10
0
0
0
0
10
0
% S
% Thr:
0
10
0
0
10
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
10
0
0
0
0
19
0
0
10
10
0
10
0
0
% V
% Trp:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _