Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUS2L All Species: 29.39
Human Site: Y274 Identified Species: 49.74
UniProt: Q9NX74 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX74 NP_060273.1 493 55050 Y274 Y I R Y A V Q Y D N H Y T N T
Chimpanzee Pan troglodytes XP_001166638 493 55074 Y274 Y I R Y A V Q Y D N H Y T N T
Rhesus Macaque Macaca mulatta XP_001097732 492 55071 Y273 Y I R Y A V Q Y D N H Y T N T
Dog Lupus familis XP_546866 560 62189 Y341 Y I R Y A V Q Y E N H Y T N T
Cat Felis silvestris
Mouse Mus musculus Q9D7B1 493 55306 Y274 Y I R Y A V Q Y D N H Y T N T
Rat Rattus norvegicus Q8K582 438 49691 S246 P A L F E G R S P A V W E L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414079 518 58426 Y301 Y I K Y A V R Y D N H Y T N T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001342694 504 56694 Y279 Y I T Y A V R Y D N N P F N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572950 473 52758 R281 E L I E K Y L R L C V D Y D N
Honey Bee Apis mellifera XP_393745 457 52069 Y265 M E D V I K S Y L K Y A V D C
Nematode Worm Caenorhab. elegans NP_493554 436 48980 S244 R K A L S T P S I F R R E G C
Sea Urchin Strong. purpuratus XP_001190481 278 31026 G86 D R L V F Q M G T A D A Q R A
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132459 320 35812 P128 G A A L L S K P E L I H D I L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53720 384 42798 T192 L T V H C R K T E M R N R E Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.7 80.1 N.A. 90.2 22.5 N.A. N.A. 67.5 N.A. 60.9 N.A. 44.4 42.5 37.9 38.7
Protein Similarity: 100 99.5 98.5 84.6 N.A. 95.3 39.7 N.A. N.A. 79.7 N.A. 76.9 N.A. 60.4 59.4 56.5 48
P-Site Identity: 100 100 100 93.3 N.A. 100 0 N.A. N.A. 86.6 N.A. 66.6 N.A. 0 6.6 0 0
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. N.A. 100 N.A. 80 N.A. 13.3 20 6.6 0
Percent
Protein Identity: N.A. 35.5 N.A. N.A. 30.6 N.A.
Protein Similarity: N.A. 46.6 N.A. N.A. 46.6 N.A.
P-Site Identity: N.A. 0 N.A. N.A. 0 N.A.
P-Site Similarity: N.A. 20 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 15 0 50 0 0 0 0 15 0 15 0 0 15 % A
% Cys: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 15 % C
% Asp: 8 0 8 0 0 0 0 0 43 0 8 8 8 15 0 % D
% Glu: 8 8 0 8 8 0 0 0 22 0 0 0 15 8 0 % E
% Phe: 0 0 0 8 8 0 0 0 0 8 0 0 8 0 0 % F
% Gly: 8 0 0 0 0 8 0 8 0 0 0 0 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 43 8 0 0 0 % H
% Ile: 0 50 8 0 8 0 0 0 8 0 8 0 0 8 0 % I
% Lys: 0 8 8 0 8 8 15 0 0 8 0 0 0 0 0 % K
% Leu: 8 8 15 15 8 0 8 0 15 8 0 0 0 8 8 % L
% Met: 8 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 50 8 8 0 50 8 % N
% Pro: 8 0 0 0 0 0 8 8 8 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 8 36 0 0 0 0 0 8 0 8 % Q
% Arg: 8 8 36 0 0 8 22 8 0 0 15 8 8 8 0 % R
% Ser: 0 0 0 0 8 8 8 15 0 0 0 0 0 0 0 % S
% Thr: 0 8 8 0 0 8 0 8 8 0 0 0 43 0 50 % T
% Val: 0 0 8 15 0 50 0 0 0 0 15 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 50 0 0 50 0 8 0 58 0 0 8 43 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _