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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS2L
All Species:
16.67
Human Site:
T349
Identified Species:
28.21
UniProt:
Q9NX74
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX74
NP_060273.1
493
55050
T349
T
G
E
P
A
E
D
T
S
G
V
I
K
M
A
Chimpanzee
Pan troglodytes
XP_001166638
493
55074
T349
T
G
E
P
A
E
D
T
S
G
V
I
K
M
A
Rhesus Macaque
Macaca mulatta
XP_001097732
492
55071
T348
T
G
E
P
A
E
D
T
S
G
V
I
K
M
A
Dog
Lupus familis
XP_546866
560
62189
T416
A
R
E
P
V
E
D
T
S
G
V
I
K
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7B1
493
55306
T349
V
E
E
P
A
E
D
T
S
G
I
I
K
M
A
Rat
Rattus norvegicus
Q8K582
438
49691
E321
E
D
M
A
R
Q
Q
E
G
V
R
P
A
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414079
518
58426
N376
D
D
Q
M
E
D
P
N
V
I
K
M
A
V
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001342694
504
56694
D354
E
T
P
E
L
E
D
D
V
V
I
M
P
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572950
473
52758
L356
E
V
E
P
P
E
A
L
A
K
R
Q
K
L
E
Honey Bee
Apis mellifera
XP_393745
457
52069
K340
R
S
Q
V
S
P
M
K
E
D
E
K
Q
T
Q
Nematode Worm
Caenorhab. elegans
NP_493554
436
48980
R319
E
D
V
Y
D
K
W
R
D
E
R
K
K
K
Q
Sea Urchin
Strong. purpuratus
XP_001190481
278
31026
D161
R
I
L
P
K
L
E
D
T
I
A
L
A
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132459
320
35812
I203
D
V
V
S
A
L
S
I
P
V
I
A
N
G
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53720
384
42798
E267
D
H
T
S
K
P
S
E
D
G
P
S
W
V
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
80.1
N.A.
90.2
22.5
N.A.
N.A.
67.5
N.A.
60.9
N.A.
44.4
42.5
37.9
38.7
Protein Similarity:
100
99.5
98.5
84.6
N.A.
95.3
39.7
N.A.
N.A.
79.7
N.A.
76.9
N.A.
60.4
59.4
56.5
48
P-Site Identity:
100
100
100
80
N.A.
80
0
N.A.
N.A.
0
N.A.
13.3
N.A.
26.6
0
6.6
6.6
P-Site Similarity:
100
100
100
80
N.A.
86.6
6.6
N.A.
N.A.
26.6
N.A.
33.3
N.A.
40
20
13.3
26.6
Percent
Protein Identity:
N.A.
35.5
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
46.6
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
36
0
8
0
8
0
8
8
22
0
36
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
22
0
0
8
8
43
15
15
8
0
0
0
8
8
% D
% Glu:
29
8
43
8
8
50
8
15
8
8
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
22
0
0
0
0
0
0
8
43
0
0
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
15
22
36
0
0
0
% I
% Lys:
0
0
0
0
15
8
0
8
0
8
8
15
50
15
0
% K
% Leu:
0
0
8
0
8
15
0
8
0
0
0
8
0
8
0
% L
% Met:
0
0
8
8
0
0
8
0
0
0
0
15
0
36
8
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% N
% Pro:
0
0
8
50
8
15
8
0
8
0
8
8
8
0
0
% P
% Gln:
0
0
15
0
0
8
8
0
0
0
0
8
8
0
15
% Q
% Arg:
15
8
0
0
8
0
0
8
0
0
22
0
0
0
15
% R
% Ser:
0
8
0
15
8
0
15
0
36
0
0
8
0
0
0
% S
% Thr:
22
8
8
0
0
0
0
36
8
0
0
0
0
8
0
% T
% Val:
8
15
15
8
8
0
0
0
15
22
29
0
0
22
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _