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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS2L
All Species:
17.88
Human Site:
S447
Identified Species:
30.26
UniProt:
Q9NX74
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX74
NP_060273.1
493
55050
S447
R
L
G
E
E
S
P
S
L
H
K
R
K
R
E
Chimpanzee
Pan troglodytes
XP_001166638
493
55074
S447
R
L
G
E
E
S
P
S
L
H
K
R
K
R
E
Rhesus Macaque
Macaca mulatta
XP_001097732
492
55071
S446
R
L
G
E
E
S
P
S
L
H
K
R
K
R
E
Dog
Lupus familis
XP_546866
560
62189
S514
R
L
G
E
E
N
P
S
W
H
K
R
K
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7B1
493
55306
S447
R
L
G
E
E
S
P
S
L
N
K
R
K
R
E
Rat
Rattus norvegicus
Q8K582
438
49691
G415
C
V
F
N
L
C
R
G
C
C
K
K
R
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414079
518
58426
H472
K
L
C
E
G
E
N
H
L
I
N
K
R
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001342694
504
56694
G450
R
I
G
E
E
H
S
G
L
V
N
K
R
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572950
473
52758
A450
K
Q
A
E
Q
G
A
A
L
V
A
L
L
H
L
Honey Bee
Apis mellifera
XP_393745
457
52069
A434
K
W
A
E
Q
G
A
A
L
V
C
L
F
S
L
Nematode Worm
Caenorhab. elegans
NP_493554
436
48980
Q413
P
N
L
R
M
A
E
Q
V
A
A
L
A
A
L
Sea Urchin
Strong. purpuratus
XP_001190481
278
31026
L255
I
F
R
K
E
G
K
L
P
N
H
D
V
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132459
320
35812
D297
G
K
G
V
I
K
C
D
T
S
E
D
L
A
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53720
384
42798
K361
A
N
A
I
A
K
Q
K
R
K
Q
T
D
H
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
80.1
N.A.
90.2
22.5
N.A.
N.A.
67.5
N.A.
60.9
N.A.
44.4
42.5
37.9
38.7
Protein Similarity:
100
99.5
98.5
84.6
N.A.
95.3
39.7
N.A.
N.A.
79.7
N.A.
76.9
N.A.
60.4
59.4
56.5
48
P-Site Identity:
100
100
100
86.6
N.A.
93.3
6.6
N.A.
N.A.
20
N.A.
33.3
N.A.
13.3
13.3
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
26.6
N.A.
N.A.
46.6
N.A.
60
N.A.
33.3
33.3
13.3
26.6
Percent
Protein Identity:
N.A.
35.5
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
46.6
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
22
0
8
8
15
15
0
8
15
0
8
29
0
% A
% Cys:
8
0
8
0
0
8
8
0
8
8
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
15
8
0
0
% D
% Glu:
0
0
0
65
50
8
8
0
0
0
8
0
0
0
36
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
8
% F
% Gly:
8
0
50
0
8
22
0
15
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
29
8
0
0
15
0
% H
% Ile:
8
8
0
8
8
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
22
8
0
8
0
15
8
8
0
8
43
22
36
15
8
% K
% Leu:
0
43
8
0
8
0
0
8
58
0
0
22
15
0
22
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
8
0
8
8
0
0
15
15
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
36
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
15
0
8
8
0
0
8
0
0
0
0
% Q
% Arg:
43
0
8
8
0
0
8
0
8
0
0
36
22
36
22
% R
% Ser:
0
0
0
0
0
29
8
36
0
8
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% T
% Val:
0
8
0
8
0
0
0
0
8
22
0
0
8
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _