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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS2L
All Species:
9.09
Human Site:
S335
Identified Species:
15.38
UniProt:
Q9NX74
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX74
NP_060273.1
493
55050
S335
D
A
Q
Q
A
R
L
S
A
K
T
S
E
Q
T
Chimpanzee
Pan troglodytes
XP_001166638
493
55074
S335
D
A
Q
Q
A
R
L
S
A
K
T
S
E
E
T
Rhesus Macaque
Macaca mulatta
XP_001097732
492
55071
S334
D
A
Q
R
A
K
L
S
A
R
T
S
E
E
T
Dog
Lupus familis
XP_546866
560
62189
L402
N
A
R
R
A
E
L
L
A
R
T
P
E
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7B1
493
55306
L335
D
A
R
R
A
D
L
L
A
K
T
P
E
A
V
Rat
Rattus norvegicus
Q8K582
438
49691
A307
G
V
A
A
V
S
Q
A
L
K
L
R
C
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414079
518
58426
E362
E
A
K
K
T
S
L
E
T
K
K
Q
D
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001342694
504
56694
Q340
E
S
R
R
A
S
L
Q
A
S
E
D
L
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572950
473
52758
M342
K
Q
R
E
L
K
T
M
G
N
S
G
R
A
E
Honey Bee
Apis mellifera
XP_393745
457
52069
E326
Y
L
K
K
K
E
F
E
E
K
G
L
L
G
R
Nematode Worm
Caenorhab. elegans
NP_493554
436
48980
I305
A
A
G
S
V
L
Q
I
C
K
A
F
G
M
E
Sea Urchin
Strong. purpuratus
XP_001190481
278
31026
I147
T
L
V
Q
G
V
K
I
P
V
T
C
K
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132459
320
35812
A189
K
D
R
P
R
D
L
A
K
W
D
E
I
A
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53720
384
42798
E253
G
M
I
A
E
C
A
E
R
D
P
T
V
F
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
80.1
N.A.
90.2
22.5
N.A.
N.A.
67.5
N.A.
60.9
N.A.
44.4
42.5
37.9
38.7
Protein Similarity:
100
99.5
98.5
84.6
N.A.
95.3
39.7
N.A.
N.A.
79.7
N.A.
76.9
N.A.
60.4
59.4
56.5
48
P-Site Identity:
100
93.3
73.3
40
N.A.
53.3
13.3
N.A.
N.A.
20
N.A.
20
N.A.
0
6.6
13.3
13.3
P-Site Similarity:
100
100
100
66.6
N.A.
66.6
20
N.A.
N.A.
53.3
N.A.
46.6
N.A.
26.6
20
13.3
20
Percent
Protein Identity:
N.A.
35.5
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
46.6
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
50
8
15
43
0
8
15
43
0
8
0
0
29
8
% A
% Cys:
0
0
0
0
0
8
0
0
8
0
0
8
8
0
0
% C
% Asp:
29
8
0
0
0
15
0
0
0
8
8
8
8
0
22
% D
% Glu:
15
0
0
8
8
15
0
22
8
0
8
8
36
22
29
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
8
0
% F
% Gly:
15
0
8
0
8
0
0
0
8
0
8
8
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
15
0
0
0
0
8
8
0
% I
% Lys:
15
0
15
15
8
15
8
0
8
50
8
0
8
0
0
% K
% Leu:
0
15
0
0
8
8
58
15
8
0
8
8
15
0
0
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
8
0
8
15
0
0
0
% P
% Gln:
0
8
22
22
0
0
15
8
0
0
0
8
0
15
0
% Q
% Arg:
0
0
36
29
8
15
0
0
8
15
0
8
8
0
15
% R
% Ser:
0
8
0
8
0
22
0
22
0
8
8
22
0
8
0
% S
% Thr:
8
0
0
0
8
0
8
0
8
0
43
8
0
0
22
% T
% Val:
0
8
8
0
15
8
0
0
0
8
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _