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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNL4B
All Species:
42.98
Human Site:
Y146
Identified Species:
72.73
UniProt:
Q9NX01
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX01
NP_001135789.1
149
17015
Y146
I
P
K
Y
D
L
L
Y
Q
D
I
_
_
_
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103949
149
17022
Y146
I
P
K
Y
D
L
L
Y
Q
D
I
_
_
_
_
Dog
Lupus familis
XP_853407
149
17054
Y146
I
P
K
Y
D
L
L
Y
Q
D
I
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUH1
149
16875
Y146
V
P
K
Y
D
L
L
Y
Q
D
I
_
_
_
_
Rat
Rattus norvegicus
NP_001013913
149
17036
Y146
I
P
K
Y
D
L
L
Y
Q
D
I
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416612
149
16980
Y146
I
P
K
Y
D
L
L
Y
Q
G
I
_
_
_
_
Frog
Xenopus laevis
NP_001089306
149
17095
Y146
I
P
K
Y
D
L
L
Y
L
G
V
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_001032200
149
17015
Y146
I
P
K
Y
D
L
L
Y
H
D
I
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624360
142
16840
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780032
149
17110
Y146
V
H
Q
Y
E
L
L
Y
Q
D
I
_
_
_
_
Poplar Tree
Populus trichocarpa
XP_002298799
153
17406
Y150
I
P
K
Y
E
L
L
Y
K
N
L
_
_
_
_
Maize
Zea mays
NP_001147284
152
17193
F149
I
P
R
F
Q
L
L
F
K
D
V
_
_
_
_
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189117
159
18300
Y156
I
P
K
Y
Q
L
V
Y
K
D
V
_
_
_
_
Baker's Yeast
Sacchar. cerevisiae
Q06819
143
16758
H139
V
S
P
Y
D
Y
N
H
K
R
V
S
_
_
_
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
97.3
N.A.
95.3
97.9
N.A.
N.A.
89.2
89.2
83.8
N.A.
N.A.
36.9
N.A.
73.8
Protein Similarity:
100
N.A.
99.3
97.3
N.A.
96.6
98.6
N.A.
N.A.
93.2
95.9
93.2
N.A.
N.A.
63
N.A.
87.2
P-Site Identity:
100
N.A.
100
100
N.A.
90.9
100
N.A.
N.A.
90.9
72.7
90.9
N.A.
N.A.
0
N.A.
63.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
90.9
81.8
90.9
N.A.
N.A.
0
N.A.
90.9
Percent
Protein Identity:
58.1
58.5
N.A.
56.6
31.5
N.A.
Protein Similarity:
74.5
76.3
N.A.
74.8
59
N.A.
P-Site Identity:
63.6
45.4
N.A.
63.6
16.6
N.A.
P-Site Similarity:
100
90.9
N.A.
90.9
50
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
65
0
0
0
0
65
0
0
0
0
0
% D
% Glu:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
72
0
0
0
0
0
0
0
0
0
58
0
0
0
0
% I
% Lys:
0
0
72
0
0
0
0
0
29
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
86
79
0
8
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% N
% Pro:
0
79
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
15
0
0
0
50
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
22
0
0
0
0
0
8
0
0
0
29
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
86
0
8
0
79
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
86
93
93
93
% _