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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNL4B
All Species:
31.82
Human Site:
S46
Identified Species:
53.85
UniProt:
Q9NX01
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX01
NP_001135789.1
149
17015
S46
L
Q
L
D
D
I
L
S
K
T
S
S
D
L
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103949
149
17022
S46
L
Q
L
D
D
I
L
S
K
T
S
S
D
L
S
Dog
Lupus familis
XP_853407
149
17054
S46
L
Q
L
D
D
I
L
S
K
T
S
P
D
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUH1
149
16875
S46
L
Q
L
D
D
I
L
S
K
T
S
A
D
L
S
Rat
Rattus norvegicus
NP_001013913
149
17036
S46
L
Q
L
D
D
I
L
S
K
T
S
A
D
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416612
149
16980
A46
L
Q
L
D
D
I
L
A
K
T
A
H
D
L
S
Frog
Xenopus laevis
NP_001089306
149
17095
S46
L
Q
L
D
D
I
L
S
K
T
S
H
D
L
S
Zebra Danio
Brachydanio rerio
NP_001032200
149
17015
S46
L
Q
I
D
E
I
L
S
K
T
A
H
D
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624360
142
16840
K40
D
W
D
P
M
C
M
K
M
D
E
V
L
Y
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780032
149
17110
S46
M
Q
L
D
E
I
L
S
K
T
S
E
D
L
G
Poplar Tree
Populus trichocarpa
XP_002298799
153
17406
S50
L
D
D
I
L
S
K
S
A
R
E
V
S
K
F
Maize
Zea mays
NP_001147284
152
17193
S49
L
D
D
I
L
D
K
S
S
W
D
I
S
K
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189117
159
18300
S56
H
D
E
I
L
A
K
S
V
R
D
V
S
K
F
Baker's Yeast
Sacchar. cerevisiae
Q06819
143
16758
C39
G
R
K
N
D
R
Q
C
M
I
M
D
E
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
97.3
N.A.
95.3
97.9
N.A.
N.A.
89.2
89.2
83.8
N.A.
N.A.
36.9
N.A.
73.8
Protein Similarity:
100
N.A.
99.3
97.3
N.A.
96.6
98.6
N.A.
N.A.
93.2
95.9
93.2
N.A.
N.A.
63
N.A.
87.2
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
93.3
73.3
N.A.
N.A.
0
N.A.
73.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
N.A.
13.3
N.A.
86.6
Percent
Protein Identity:
58.1
58.5
N.A.
56.6
31.5
N.A.
Protein Similarity:
74.5
76.3
N.A.
74.8
59
N.A.
P-Site Identity:
13.3
13.3
N.A.
6.6
13.3
N.A.
P-Site Similarity:
13.3
13.3
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
8
0
15
15
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
22
22
65
58
8
0
0
0
8
15
8
65
0
0
% D
% Glu:
0
0
8
0
15
0
0
0
0
0
15
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
22
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
22
0
0
0
% H
% Ile:
0
0
8
22
0
65
0
0
0
8
0
8
0
0
0
% I
% Lys:
0
0
8
0
0
0
22
8
65
0
0
0
0
22
0
% K
% Leu:
72
0
58
0
22
0
65
0
0
0
0
0
8
72
8
% L
% Met:
8
0
0
0
8
0
8
0
15
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
65
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
0
15
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
79
8
0
50
15
22
0
58
% S
% Thr:
0
0
0
0
0
0
0
0
0
65
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
22
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _