KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRAK4
All Species:
18.18
Human Site:
T209
Identified Species:
36.36
UniProt:
Q9NWZ3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWZ3
NP_001107654.1
460
51530
T209
K
G
Y
V
N
N
T
T
V
A
V
K
K
L
A
Chimpanzee
Pan troglodytes
XP_001166114
460
51588
T209
K
G
Y
V
N
N
T
T
V
A
V
K
K
L
A
Rhesus Macaque
Macaca mulatta
NP_001129573
460
51601
T209
K
G
Y
V
N
N
A
T
V
A
V
K
K
L
A
Dog
Lupus familis
XP_543727
460
51521
T209
K
G
Y
V
N
N
K
T
V
A
V
K
K
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4K2
459
50853
I209
K
G
C
V
N
N
T
I
V
A
V
K
K
L
G
Rat
Rattus norvegicus
NP_001100261
461
51050
T211
K
G
C
V
N
N
T
T
V
A
V
K
K
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521647
280
31332
T80
D
W
G
T
S
N
C
T
V
G
D
L
V
D
L
Chicken
Gallus gallus
NP_001025909
373
40585
Q173
C
E
K
Q
Q
P
I
Q
E
K
E
V
T
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956457
382
41751
G182
S
S
W
D
S
S
Q
G
F
H
T
F
S
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784716
406
45182
L203
Q
L
C
L
V
Y
E
L
I
T
G
G
A
L
R
Poplar Tree
Populus trichocarpa
XP_002322185
562
63055
E281
I
G
T
L
K
E
R
E
V
A
I
K
K
M
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_198715
880
97935
K554
G
A
T
L
V
A
V
K
R
L
E
I
T
S
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.6
92.8
N.A.
83.9
84.3
N.A.
45.2
47.3
N.A.
39.1
N.A.
N.A.
N.A.
N.A.
33.9
Protein Similarity:
100
99.5
99.1
96.3
N.A.
90.8
91.9
N.A.
51.9
58.2
N.A.
54.7
N.A.
N.A.
N.A.
N.A.
51
P-Site Identity:
100
100
93.3
93.3
N.A.
80
86.6
N.A.
20
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
86.6
N.A.
26.6
0
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
28.1
N.A.
N.A.
21.5
N.A.
N.A.
Protein Similarity:
47.5
N.A.
N.A.
34.4
N.A.
N.A.
P-Site Identity:
33.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
9
0
0
59
0
0
9
0
34
% A
% Cys:
9
0
25
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
0
0
0
0
9
0
0
9
0
% D
% Glu:
0
9
0
0
0
9
9
9
9
0
17
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% F
% Gly:
9
59
9
0
0
0
0
9
0
9
9
9
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% H
% Ile:
9
0
0
0
0
0
9
9
9
0
9
9
0
0
0
% I
% Lys:
50
0
9
0
9
0
9
9
0
9
0
59
59
0
9
% K
% Leu:
0
9
0
25
0
0
0
9
0
9
0
9
0
67
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
50
59
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
9
9
0
9
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
9
% R
% Ser:
9
9
0
0
17
9
0
0
0
0
0
0
9
17
0
% S
% Thr:
0
0
17
9
0
0
34
50
0
9
9
0
17
0
0
% T
% Val:
0
0
0
50
17
0
9
0
67
0
50
9
9
0
9
% V
% Trp:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
34
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _