KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MERIT40
All Species:
22.42
Human Site:
S270
Identified Species:
54.81
UniProt:
Q9NWV8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWV8
NP_001028721.1
329
36560
S270
D
M
F
A
F
M
G
S
L
D
T
K
G
T
S
Chimpanzee
Pan troglodytes
XP_512482
329
36513
S270
D
M
F
A
F
M
G
S
L
D
T
K
G
T
S
Rhesus Macaque
Macaca mulatta
XP_001113414
329
36525
S270
D
M
F
A
F
M
G
S
L
D
T
K
G
T
S
Dog
Lupus familis
XP_533881
336
37413
S277
D
M
F
A
F
M
G
S
L
D
T
K
G
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3UI43
333
36775
S274
D
M
F
A
F
M
G
S
L
D
T
K
G
A
S
Rat
Rattus norvegicus
Q5XIJ6
334
36860
S275
D
M
F
A
F
M
G
S
L
D
T
K
G
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DJG6
328
36935
D271
F
G
F
F
S
S
L
D
S
K
G
T
S
Y
K
Zebra Danio
Brachydanio rerio
Q6AXK4
370
40883
E312
D
V
Y
A
S
F
C
E
L
D
T
K
G
M
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120759
190
21723
V146
N
F
S
Y
I
L
E
V
G
R
N
A
A
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793273
338
38040
D291
D
I
Y
D
V
F
L
D
L
D
K
N
N
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.7
93.1
N.A.
89.7
88.3
N.A.
N.A.
N.A.
72.3
58.9
N.A.
N.A.
23.7
N.A.
35.2
Protein Similarity:
100
99.3
99
94.9
N.A.
94.5
94
N.A.
N.A.
N.A.
81.1
69.7
N.A.
N.A.
37.9
N.A.
52.6
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
N.A.
6.6
46.6
N.A.
N.A.
0
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
N.A.
6.6
60
N.A.
N.A.
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
70
0
0
0
0
0
0
0
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% C
% Asp:
80
0
0
10
0
0
0
20
0
80
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% E
% Phe:
10
10
70
10
60
20
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
60
0
10
0
10
0
70
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
10
70
0
10
10
% K
% Leu:
0
0
0
0
0
10
20
0
80
0
0
0
0
0
10
% L
% Met:
0
60
0
0
0
60
0
0
0
0
0
0
0
10
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
10
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
10
0
20
10
0
60
10
0
0
0
10
0
70
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
70
10
0
60
0
% T
% Val:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
10
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _