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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IFT57
All Species:
27.58
Human Site:
S273
Identified Species:
46.67
UniProt:
Q9NWB7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWB7
NP_060480.1
429
49108
S273
D
Q
M
H
Q
H
R
S
G
I
E
S
A
L
K
Chimpanzee
Pan troglodytes
XP_526260
429
49046
S273
D
Q
M
H
Q
H
K
S
G
I
E
S
A
L
K
Rhesus Macaque
Macaca mulatta
XP_001101043
429
48998
S273
D
Q
M
H
Q
H
K
S
G
I
E
S
A
L
K
Dog
Lupus familis
XP_535730
570
64477
S414
D
Q
M
H
Q
H
K
S
G
I
E
S
A
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXG3
429
48753
S273
D
Q
M
H
Q
H
K
S
G
I
E
S
A
L
K
Rat
Rattus norvegicus
NP_001100563
429
48762
S273
D
Q
M
H
Q
H
K
S
G
I
E
S
A
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518621
415
47398
S263
Q
H
K
E
A
I
E
S
A
L
K
E
T
K
G
Chicken
Gallus gallus
XP_416624
532
60520
D376
D
Q
M
H
Q
H
K
D
G
I
E
S
S
L
K
Frog
Xenopus laevis
A9ULY7
411
47255
T259
Q
H
R
D
G
I
D
T
S
L
K
E
T
K
G
Zebra Danio
Brachydanio rerio
Q6IVW0
407
46575
T255
Q
H
Q
D
G
I
N
T
S
L
Q
D
A
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQS5
405
47155
T253
T
H
I
S
Q
M
E
T
L
K
T
N
I
L
E
Honey Bee
Apis mellifera
XP_625220
407
47200
M255
D
Q
M
K
Q
L
R
M
N
I
A
T
N
L
T
Nematode Worm
Caenorhab. elegans
Q93833
412
46486
M260
W
R
L
H
L
E
Q
M
N
S
M
H
K
N
V
Sea Urchin
Strong. purpuratus
XP_001192285
405
46654
E253
H
L
H
K
D
G
I
E
T
A
L
S
E
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.8
69.3
N.A.
90.6
90.9
N.A.
79.7
61
73.4
62
N.A.
34.2
46.8
37
58.9
Protein Similarity:
100
99.7
99.5
72.2
N.A.
93.9
94.1
N.A.
86.7
71.9
84.3
77.8
N.A.
55.2
66.6
62.7
75.9
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
6.6
80
0
6.6
N.A.
13.3
46.6
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
93.3
20
26.6
N.A.
40
53.3
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
8
8
0
50
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
58
0
0
15
8
0
8
8
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
8
0
8
15
8
0
0
50
15
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
8
0
0
50
0
0
0
0
0
22
% G
% His:
8
29
8
58
0
50
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
0
0
22
8
0
0
58
0
0
8
0
0
% I
% Lys:
0
0
8
15
0
0
43
0
0
8
15
0
8
22
58
% K
% Leu:
0
8
8
0
8
8
0
0
8
22
8
0
0
65
0
% L
% Met:
0
0
58
0
0
8
0
15
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
15
0
0
8
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
22
58
8
0
65
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
8
0
0
0
15
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
0
0
50
15
8
0
58
8
0
0
% S
% Thr:
8
0
0
0
0
0
0
22
8
0
8
8
15
8
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _