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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM51
All Species:
26.36
Human Site:
Y239
Identified Species:
64.44
UniProt:
Q9NW97
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW97
NP_001129688.1
253
27759
Y239
P
L
T
P
P
P
Q
Y
D
E
V
Q
E
K
A
Chimpanzee
Pan troglodytes
XP_001148634
212
23357
D199
L
T
P
P
P
Q
Y
D
E
V
Q
E
K
A
P
Rhesus Macaque
Macaca mulatta
XP_001082343
251
27509
Y237
P
L
T
P
P
P
Q
Y
D
E
V
Q
E
K
A
Dog
Lupus familis
XP_848976
250
27565
Y236
P
L
T
P
P
P
Q
Y
D
E
V
Q
E
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG1
249
27380
Y235
P
L
T
P
P
P
L
Y
D
E
V
Q
A
K
A
Rat
Rattus norvegicus
NP_001102743
249
27290
Y235
P
L
T
P
P
P
Q
Y
D
E
V
Q
A
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520545
247
27452
Y233
P
L
T
P
P
P
Q
Y
D
E
V
Q
E
K
A
Chicken
Gallus gallus
XP_001234352
250
27303
Y236
P
L
T
P
P
P
K
Y
E
D
I
Q
E
K
A
Frog
Xenopus laevis
NP_001084526
233
25635
P220
I
E
P
L
T
P
P
P
Q
Y
E
E
K
P
L
Zebra Danio
Brachydanio rerio
NP_001096087
225
24340
Q212
E
P
L
T
P
P
P
Q
Y
E
D
K
P
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
98
88.9
N.A.
84.9
86.5
N.A.
77.8
64.8
51.3
36.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
83.7
99.2
92.8
N.A.
89.7
90.5
N.A.
87.3
77
63.2
52.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
86.6
93.3
N.A.
100
73.3
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
86.6
93.3
N.A.
100
100
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
20
10
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
60
10
10
0
0
0
0
% D
% Glu:
10
10
0
0
0
0
0
0
20
70
10
20
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
10
20
70
0
% K
% Leu:
10
70
10
10
0
0
10
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
70
10
20
80
90
90
20
10
0
0
0
0
10
20
10
% P
% Gln:
0
0
0
0
0
10
50
10
10
0
10
70
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
10
70
10
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
60
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
70
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _