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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR70
All Species:
34.85
Human Site:
S561
Identified Species:
51.11
UniProt:
Q9NW82
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW82
NP_060504.1
654
73201
S561
D
R
L
D
P
L
K
S
H
K
P
E
P
P
V
Chimpanzee
Pan troglodytes
XP_517797
733
81613
S640
D
R
L
D
P
L
K
S
H
K
P
E
P
P
V
Rhesus Macaque
Macaca mulatta
XP_001094466
730
81405
S637
D
R
L
D
P
L
K
S
H
K
P
E
P
P
V
Dog
Lupus familis
XP_546343
767
84520
S674
D
R
L
D
P
L
K
S
H
K
P
E
P
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3TWF6
657
73100
S564
D
R
L
D
P
L
K
S
H
K
P
E
P
P
V
Rat
Rattus norvegicus
Q5EB92
655
72817
S562
D
R
L
D
P
L
K
S
H
K
P
E
P
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512414
423
47462
G343
P
V
A
G
P
G
R
G
G
R
V
G
T
H
G
Chicken
Gallus gallus
NP_001026621
387
42207
E307
R
T
W
D
V
N
N
E
K
K
H
K
S
V
F
Frog
Xenopus laevis
Q6GPP0
622
68798
S529
D
R
L
D
P
V
K
S
H
K
P
E
P
P
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1J3
655
73589
S562
A
R
M
D
P
V
K
S
Q
R
P
D
L
P
I
Honey Bee
Apis mellifera
XP_393688
664
74562
S575
D
R
L
D
P
V
K
S
R
R
P
D
L
P
I
Nematode Worm
Caenorhab. elegans
O16519
620
69027
R508
W
R
I
K
K
Y
L
R
M
Q
D
N
K
L
R
Sea Urchin
Strong. purpuratus
XP_794637
641
71917
R531
L
C
M
V
K
K
R
R
N
R
V
E
P
D
I
Poplar Tree
Populus trichocarpa
XP_002320613
647
71276
K564
K
D
P
L
K
S
H
K
P
E
L
P
M
T
G
Maize
Zea mays
NP_001147117
622
68359
K539
K
D
P
L
K
S
H
K
P
E
A
P
V
N
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_179623
648
71183
K561
K
D
P
M
K
S
H
K
P
E
I
P
M
T
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.8
88.2
81.2
N.A.
91
92.6
N.A.
55.2
40.5
74.4
N.A.
N.A.
42.1
45.4
36.8
45.2
Protein Similarity:
100
88.9
89.1
83.4
N.A.
95.1
96.6
N.A.
59.7
48.4
84.2
N.A.
N.A.
63
64.3
55.6
63.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
13.3
93.3
N.A.
N.A.
46.6
60
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
20
100
N.A.
N.A.
80
86.6
20
46.6
Percent
Protein Identity:
35.9
38.8
N.A.
37.3
N.A.
N.A.
Protein Similarity:
53.2
57.3
N.A.
57.9
N.A.
N.A.
P-Site Identity:
0
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
6.6
6.6
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
19
0
63
0
0
0
0
0
0
7
13
0
7
0
% D
% Glu:
0
0
0
0
0
0
0
7
0
19
0
50
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
7
0
7
0
7
7
0
0
7
0
0
25
% G
% His:
0
0
0
0
0
0
19
0
44
0
7
0
0
7
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
19
% I
% Lys:
19
0
0
7
32
7
57
19
7
50
0
7
7
0
0
% K
% Leu:
7
0
50
13
0
38
7
0
0
0
7
0
13
7
0
% L
% Met:
0
0
13
7
0
0
0
0
7
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
7
7
0
7
0
0
7
0
7
0
% N
% Pro:
7
0
19
0
63
0
0
0
19
0
57
19
50
57
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% Q
% Arg:
7
63
0
0
0
0
13
13
7
25
0
0
0
0
7
% R
% Ser:
0
0
0
0
0
19
0
57
0
0
0
0
7
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
0
0
0
7
13
0
% T
% Val:
0
7
0
7
7
19
0
0
0
0
13
0
7
7
44
% V
% Trp:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _