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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NLE1
All Species:
26.36
Human Site:
S133
Identified Species:
44.62
UniProt:
Q9NVX2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVX2
NP_001014445.1
485
53266
S133
G
K
Y
L
A
S
G
S
G
D
T
T
V
R
F
Chimpanzee
Pan troglodytes
XP_001174396
452
49610
V100
Q
P
Q
A
I
F
R
V
R
A
V
T
R
C
T
Rhesus Macaque
Macaca mulatta
XP_001113853
485
53205
S133
G
K
Y
L
A
S
G
S
G
D
T
T
V
R
F
Dog
Lupus familis
XP_548262
468
51088
S119
G
K
Y
L
A
S
G
S
G
D
T
T
V
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ4
485
53130
S133
G
K
Y
L
A
S
G
S
G
D
T
T
V
R
F
Rat
Rattus norvegicus
Q5BK30
415
45841
Q76
R
L
Q
E
K
L
R
Q
H
C
D
H
N
F
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415857
482
53449
S130
G
K
Y
L
A
S
G
S
G
D
T
T
V
R
F
Frog
Xenopus laevis
Q5FWQ6
415
45899
Q76
R
L
Q
E
K
I
G
Q
Q
D
S
R
Q
F
Y
Zebra Danio
Brachydanio rerio
Q803D2
410
46511
K71
K
V
M
E
L
E
S
K
L
N
E
A
K
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
P21
V
V
H
P
P
Q
Q
P
L
P
T
A
P
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
P37
G
G
S
S
A
P
A
P
S
T
S
P
N
S
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148971
471
52128
S125
G
K
S
L
A
S
G
S
G
D
T
T
V
R
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLX9
473
52879
S128
G
K
Q
L
A
S
G
S
G
D
T
T
V
R
L
Baker's Yeast
Sacchar. cerevisiae
P25382
515
57007
A163
S
S
R
M
V
T
G
A
G
D
N
T
A
R
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
98.3
86.8
N.A.
95.4
25.3
N.A.
N.A.
83.3
24.5
22.6
N.A.
25.5
N.A.
24.5
N.A.
Protein Similarity:
100
90.5
99.1
90.5
N.A.
97.9
43.7
N.A.
N.A.
91.5
44.5
41.2
N.A.
40.2
N.A.
40.8
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
0
N.A.
N.A.
100
13.3
0
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
6.6
N.A.
N.A.
100
26.6
6.6
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
57.9
N.A.
55
45.6
N.A.
Protein Similarity:
N.A.
73.2
N.A.
71.5
64.4
N.A.
P-Site Identity:
N.A.
93.3
N.A.
86.6
33.3
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
86.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
58
0
8
8
0
8
0
15
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
65
8
0
0
0
0
% D
% Glu:
0
0
0
22
0
8
0
0
0
0
8
0
0
8
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
15
43
% F
% Gly:
58
8
0
0
0
0
65
0
58
0
0
0
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
15
% I
% Lys:
8
50
0
0
15
0
0
8
0
0
0
0
8
0
0
% K
% Leu:
0
15
0
50
8
8
0
0
15
0
0
0
0
0
8
% L
% Met:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
8
0
15
0
0
% N
% Pro:
0
8
0
8
8
8
0
15
0
8
0
8
8
0
0
% P
% Gln:
8
0
29
0
0
8
8
15
8
0
0
0
8
0
0
% Q
% Arg:
15
0
8
0
0
0
15
0
8
0
0
8
8
58
0
% R
% Ser:
8
8
15
8
0
50
8
50
8
0
15
0
0
15
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
58
65
0
0
8
% T
% Val:
8
15
0
0
8
0
0
8
0
0
8
0
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
36
0
0
0
0
0
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _