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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THAP1
All Species:
31.21
Human Site:
T59
Identified Species:
85.83
UniProt:
Q9NVV9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVV9
NP_060575.1
213
24944
T59
S
I
C
S
E
H
F
T
P
D
C
F
K
R
E
Chimpanzee
Pan troglodytes
XP_514343
239
27036
R60
V
I
C
S
E
H
F
R
P
E
C
F
S
A
F
Rhesus Macaque
Macaca mulatta
XP_001099355
212
24812
T59
S
I
C
S
E
H
F
T
P
D
C
F
K
R
E
Dog
Lupus familis
XP_848435
213
24972
T59
S
I
C
S
E
H
F
T
P
D
C
F
K
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHW1
210
24593
T59
S
I
C
S
E
H
F
T
P
D
C
F
K
R
E
Rat
Rattus norvegicus
Q5U208
210
24670
T59
S
I
C
S
E
H
F
T
P
D
C
F
K
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509715
252
29755
T100
S
I
C
S
E
H
F
T
P
D
C
F
K
R
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U560
225
26180
S59
S
I
C
S
D
H
F
S
A
D
C
F
K
R
E
Zebra Danio
Brachydanio rerio
Q1JPT7
225
25689
T59
N
I
C
S
Q
H
F
T
S
D
C
F
K
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.7
99.5
97.6
N.A.
92.4
92
N.A.
66.6
N.A.
64
48.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
42.6
99.5
99
N.A.
94.3
94.3
N.A.
74.5
N.A.
75.5
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
100
100
N.A.
100
100
N.A.
100
N.A.
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% A
% Cys:
0
0
100
0
0
0
0
0
0
0
100
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
0
0
89
0
0
0
0
0
% D
% Glu:
0
0
0
0
78
0
0
0
0
12
0
0
0
0
89
% E
% Phe:
0
0
0
0
0
0
100
0
0
0
0
100
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
89
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
78
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
0
0
78
0
% R
% Ser:
78
0
0
100
0
0
0
12
12
0
0
0
12
0
0
% S
% Thr:
0
0
0
0
0
0
0
78
0
0
0
0
0
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _