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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCCD1
All Species:
24.24
Human Site:
S252
Identified Species:
44.44
UniProt:
Q9NVR7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVR7
NP_001127887.1
557
63530
S252
S
K
I
S
K
T
F
S
F
Y
K
L
E
T
W
Chimpanzee
Pan troglodytes
XP_516930
557
63610
S252
S
K
I
S
K
T
F
S
F
Y
K
L
E
T
W
Rhesus Macaque
Macaca mulatta
XP_001088550
636
71255
S329
S
K
I
S
K
T
F
S
F
Y
K
L
E
T
W
Dog
Lupus familis
XP_545241
557
63480
S252
S
R
I
S
K
T
F
S
F
Y
K
L
E
A
W
Cat
Felis silvestris
Mouse
Mus musculus
Q640P7
552
62830
K249
S
G
F
S
K
S
S
K
T
F
S
L
Y
K
L
Rat
Rattus norvegicus
Q5FVR8
569
64675
S252
S
K
I
S
K
T
F
S
L
Y
K
L
E
A
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508064
335
37651
V34
Q
V
R
K
A
A
A
V
N
R
F
R
T
L
T
Chicken
Gallus gallus
Q5ZKT1
555
62080
S250
S
K
I
S
K
T
F
S
F
P
K
L
E
N
W
Frog
Xenopus laevis
Q08AV6
547
62635
G243
Q
P
V
Q
I
K
S
G
F
I
E
T
S
G
A
Zebra Danio
Brachydanio rerio
A4QP31
582
65760
S253
S
K
L
S
C
S
Y
S
L
Q
Q
F
Q
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193557
546
60424
F243
Y
S
K
I
T
Q
A
F
S
F
K
T
F
E
S
Poplar Tree
Populus trichocarpa
XP_002331001
585
63964
A272
M
P
A
V
P
A
P
A
T
Q
V
H
D
W
I
Maize
Zea mays
NP_001168301
574
62500
I263
H
D
W
V
L
Q
H
I
A
S
A
L
E
F
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
80
93.3
N.A.
82.4
80.3
N.A.
45.7
71
58.5
54.2
N.A.
N.A.
N.A.
N.A.
47.4
Protein Similarity:
100
99.8
81.9
96.9
N.A.
91
88.5
N.A.
52
82.5
75.7
71.4
N.A.
N.A.
N.A.
N.A.
67.6
P-Site Identity:
100
100
100
86.6
N.A.
26.6
86.6
N.A.
0
86.6
6.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
40
86.6
N.A.
0
86.6
20
66.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
25.4
22.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
43.7
41.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
16
16
8
8
0
8
0
0
16
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
54
8
0
% E
% Phe:
0
0
8
0
0
0
47
8
47
16
8
8
8
8
8
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% G
% His:
8
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
47
8
8
0
0
8
0
8
0
0
0
0
8
% I
% Lys:
0
47
8
8
54
8
0
8
0
0
54
0
0
8
0
% K
% Leu:
0
0
8
0
8
0
0
0
16
0
0
62
0
8
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% N
% Pro:
0
16
0
0
8
0
8
0
0
8
0
0
0
0
0
% P
% Gln:
16
0
0
8
0
16
0
0
0
16
8
0
8
0
0
% Q
% Arg:
0
8
8
0
0
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
62
8
0
62
0
16
16
54
8
8
8
0
8
0
8
% S
% Thr:
0
0
0
0
8
47
0
0
16
0
0
16
8
24
8
% T
% Val:
0
8
8
16
0
0
0
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
47
% W
% Tyr:
8
0
0
0
0
0
8
0
0
39
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _