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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNL3L
All Species:
20.61
Human Site:
S227
Identified Species:
32.38
UniProt:
Q9NVN8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVN8
NP_061940.1
582
65573
S227
A
S
E
S
L
L
K
S
K
A
C
F
G
A
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090251
581
65443
S226
A
S
E
S
L
L
K
S
K
A
C
F
G
A
E
Dog
Lupus familis
XP_538054
649
72418
S294
A
S
E
S
L
L
K
S
K
A
C
F
G
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGG6
577
65176
S221
A
S
E
S
L
L
K
S
R
A
C
F
G
A
E
Rat
Rattus norvegicus
Q811S9
538
60642
N176
K
K
L
V
L
V
L
N
K
S
D
L
V
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510383
826
90308
S486
A
S
A
E
L
L
S
S
G
A
C
I
G
A
D
Chicken
Gallus gallus
XP_414249
686
76560
V233
Q
T
E
G
K
V
G
V
C
S
K
K
T
K
K
Frog
Xenopus laevis
Q7ZX41
542
60839
V187
M
V
E
K
W
L
Q
V
L
S
A
E
L
P
T
Zebra Danio
Brachydanio rerio
Q6DRP2
561
62883
N190
I
D
L
V
P
K
D
N
L
E
K
W
L
H
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MT06
581
65966
Y205
N
L
N
N
W
I
K
Y
F
R
R
S
G
P
V
Honey Bee
Apis mellifera
XP_001119916
573
65075
K210
S
L
P
A
V
A
F
K
A
S
T
Q
D
Q
A
Nematode Worm
Caenorhab. elegans
Q21086
556
62320
S167
P
L
G
S
R
S
K
S
V
E
D
Q
V
L
K
Sea Urchin
Strong. purpuratus
XP_783153
454
50984
G114
L
F
E
K
K
S
E
G
G
K
T
K
E
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142481
594
66162
S241
T
S
N
I
P
Q
S
S
D
C
L
G
A
E
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187361
582
65767
S229
P
S
N
M
L
Q
T
S
D
C
L
G
A
D
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
80.2
N.A.
87.1
32.6
N.A.
38.8
30.3
31.2
30.9
N.A.
36.4
39.1
37.9
36.9
Protein Similarity:
100
N.A.
97.5
84.7
N.A.
92.9
52.9
N.A.
49.8
49.1
50.5
51
N.A.
53.7
58.4
56.8
51
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
13.3
N.A.
60
6.6
13.3
0
N.A.
13.3
0
20
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
40
N.A.
66.6
33.3
26.6
13.3
N.A.
26.6
26.6
26.6
13.3
Percent
Protein Identity:
N.A.
35
N.A.
34
N.A.
N.A.
Protein Similarity:
N.A.
52.5
N.A.
51.5
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
7
7
0
7
0
0
7
34
7
0
14
34
7
% A
% Cys:
0
0
0
0
0
0
0
0
7
14
34
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
7
0
14
0
14
0
7
7
7
% D
% Glu:
0
0
47
7
0
0
7
0
0
14
0
7
7
7
27
% E
% Phe:
0
7
0
0
0
0
7
0
7
0
0
27
0
0
7
% F
% Gly:
0
0
7
7
0
0
7
7
14
0
0
14
40
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
7
0
0
7
0
7
0
0
0
0
0
7
0
0
0
% I
% Lys:
7
7
0
14
14
7
40
7
27
7
14
14
0
7
20
% K
% Leu:
7
20
14
0
47
40
7
0
14
0
14
7
14
7
0
% L
% Met:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
20
7
0
0
0
14
0
0
0
0
0
0
7
% N
% Pro:
14
0
7
0
14
0
0
0
0
0
0
0
0
20
0
% P
% Gln:
7
0
0
0
0
14
7
0
0
0
0
14
0
7
0
% Q
% Arg:
0
0
0
0
7
0
0
0
7
7
7
0
0
0
0
% R
% Ser:
7
47
0
34
0
14
14
54
0
27
0
7
0
0
0
% S
% Thr:
7
7
0
0
0
0
7
0
0
0
14
0
7
0
14
% T
% Val:
0
7
0
14
7
14
0
14
7
0
0
0
14
0
7
% V
% Trp:
0
0
0
0
14
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _