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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCI
All Species:
12.73
Human Site:
Y699
Identified Species:
21.54
UniProt:
Q9NVI1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVI1
NP_001106849.1
1328
149324
Y699
E
E
E
E
E
A
F
Y
E
D
L
D
D
I
L
Chimpanzee
Pan troglodytes
XP_001166960
1328
149462
Y699
E
E
E
E
E
A
F
Y
K
D
L
D
D
I
L
Rhesus Macaque
Macaca mulatta
XP_001092590
1268
142835
C674
L
L
C
C
I
Q
H
C
L
A
W
Y
K
N
T
Dog
Lupus familis
XP_545849
1234
138558
C640
E
P
L
D
Y
L
L
C
C
V
Q
H
C
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K368
1330
149307
Y698
E
E
E
E
E
E
L
Y
S
E
L
D
D
M
L
Rat
Rattus norvegicus
XP_001064803
1332
149518
Y700
E
Q
E
E
E
E
L
Y
H
E
L
D
D
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513065
736
82976
F142
E
L
D
K
S
A
D
F
S
Q
A
T
G
V
G
Chicken
Gallus gallus
NP_001108323
1338
149271
E702
E
E
E
D
V
G
F
E
Q
N
F
E
E
M
L
Frog
Xenopus laevis
NP_001164682
1337
149488
Q702
D
D
D
Q
T
G
C
Q
Q
D
L
N
D
I
M
Zebra Danio
Brachydanio rerio
XP_001921139
1367
152995
E701
E
E
D
V
G
G
V
E
S
E
L
Q
A
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122372
706
81709
T112
I
L
P
A
L
F
E
T
L
E
N
E
K
Y
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190805
989
110178
E395
K
A
F
Y
E
A
D
E
D
V
Q
P
P
L
K
Poplar Tree
Populus trichocarpa
XP_002315511
1406
157649
E694
F
S
L
S
Q
E
N
E
L
G
S
D
L
S
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119400
1470
164337
G700
Q
D
N
E
Q
Q
V
G
R
N
L
S
H
E
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93
81.4
N.A.
80.8
81.3
N.A.
39.7
66.9
66.9
59.4
N.A.
N.A.
20.4
N.A.
33.3
Protein Similarity:
100
99.6
94.2
86.5
N.A.
89.6
89.8
N.A.
46.9
81.6
81.5
75.9
N.A.
N.A.
33
N.A.
49.4
P-Site Identity:
100
93.3
0
6.6
N.A.
66.6
60
N.A.
13.3
33.3
26.6
26.6
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
0
26.6
N.A.
80
80
N.A.
40
73.3
73.3
46.6
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
22.7
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
29
0
0
0
8
8
0
8
0
8
% A
% Cys:
0
0
8
8
0
0
8
15
8
0
0
0
8
0
0
% C
% Asp:
8
15
22
15
0
0
15
0
8
22
0
36
36
0
0
% D
% Glu:
58
36
36
36
36
22
8
29
8
29
0
15
8
8
0
% E
% Phe:
8
0
8
0
0
8
22
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
8
22
0
8
0
8
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
8
0
8
0
0
8
8
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
0
0
0
22
8
% I
% Lys:
8
0
0
8
0
0
0
0
8
0
0
0
15
0
8
% K
% Leu:
8
22
15
0
8
8
22
0
22
0
50
0
8
15
43
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
8
% M
% Asn:
0
0
8
0
0
0
8
0
0
15
8
8
0
8
0
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
8
8
0
0
% P
% Gln:
8
8
0
8
15
15
0
8
15
8
15
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% R
% Ser:
0
8
0
8
8
0
0
0
22
0
8
8
0
8
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
8
% T
% Val:
0
0
0
8
8
0
15
0
0
15
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
29
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _