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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCI
All Species:
20
Human Site:
Y146
Identified Species:
33.85
UniProt:
Q9NVI1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVI1
NP_001106849.1
1328
149324
Y146
T
K
K
E
N
L
A
Y
G
K
G
V
L
S
G
Chimpanzee
Pan troglodytes
XP_001166960
1328
149462
Y146
T
K
K
E
N
L
A
Y
G
K
G
V
L
S
G
Rhesus Macaque
Macaca mulatta
XP_001092590
1268
142835
Y146
T
K
K
E
N
L
A
Y
G
K
G
V
L
S
G
Dog
Lupus familis
XP_545849
1234
138558
E115
T
A
L
V
A
N
K
E
N
L
A
Y
G
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K368
1330
149307
C146
T
K
K
E
V
L
A
C
G
K
G
D
L
N
G
Rat
Rattus norvegicus
XP_001064803
1332
149518
C146
T
K
K
E
G
L
T
C
G
K
G
D
L
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513065
736
82976
Chicken
Gallus gallus
NP_001108323
1338
149271
Y146
N
S
K
E
S
L
A
Y
G
K
G
E
L
N
G
Frog
Xenopus laevis
NP_001164682
1337
149488
Y145
S
S
K
E
S
L
A
Y
G
K
G
E
L
T
G
Zebra Danio
Brachydanio rerio
XP_001921139
1367
152995
Y148
S
A
T
D
A
L
A
Y
G
K
G
E
L
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122372
706
81709
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190805
989
110178
Poplar Tree
Populus trichocarpa
XP_002315511
1406
157649
N139
V
S
E
S
I
V
L
N
L
S
K
L
V
S
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119400
1470
164337
R143
S
I
L
S
G
V
T
R
V
I
T
V
D
E
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93
81.4
N.A.
80.8
81.3
N.A.
39.7
66.9
66.9
59.4
N.A.
N.A.
20.4
N.A.
33.3
Protein Similarity:
100
99.6
94.2
86.5
N.A.
89.6
89.8
N.A.
46.9
81.6
81.5
75.9
N.A.
N.A.
33
N.A.
49.4
P-Site Identity:
100
100
100
13.3
N.A.
73.3
66.6
N.A.
0
66.6
66.6
53.3
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
80
73.3
N.A.
0
80
86.6
73.3
N.A.
N.A.
0
N.A.
0
Percent
Protein Identity:
22.7
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
15
0
50
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
15
8
0
0
% D
% Glu:
0
0
8
50
0
0
0
8
0
0
0
22
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
15
0
0
0
58
0
58
0
8
0
65
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
36
50
0
0
0
8
0
0
58
8
0
0
8
0
% K
% Leu:
0
0
15
0
0
58
8
0
8
8
0
8
58
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
22
8
0
8
8
0
0
0
0
22
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
22
22
0
15
15
0
0
0
0
8
0
0
0
29
0
% S
% Thr:
43
0
8
0
0
0
15
0
0
0
8
0
0
15
0
% T
% Val:
8
0
0
8
8
15
0
0
8
0
0
29
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _