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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCI
All Species:
16.36
Human Site:
T653
Identified Species:
27.69
UniProt:
Q9NVI1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVI1
NP_001106849.1
1328
149324
T653
K
L
E
A
C
I
L
T
Q
G
D
K
I
S
L
Chimpanzee
Pan troglodytes
XP_001166960
1328
149462
T653
K
L
E
A
C
I
L
T
Q
G
D
K
I
S
L
Rhesus Macaque
Macaca mulatta
XP_001092590
1268
142835
L631
M
Q
T
L
L
S
Q
L
K
Q
F
Y
E
P
K
Dog
Lupus familis
XP_545849
1234
138558
T597
L
A
N
S
I
M
Q
T
L
L
S
Q
L
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K368
1330
149307
T652
K
L
G
A
C
V
L
T
Q
G
S
Q
I
F
L
Rat
Rattus norvegicus
XP_001064803
1332
149518
T652
K
L
G
A
C
V
L
T
Q
G
S
Q
T
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513065
736
82976
H99
W
Y
Q
S
K
M
Q
H
P
L
Q
H
E
E
D
Chicken
Gallus gallus
NP_001108323
1338
149271
A655
K
L
E
G
C
I
M
A
Q
G
D
Q
I
F
L
Frog
Xenopus laevis
NP_001164682
1337
149488
A654
K
L
E
G
C
I
T
A
Q
G
D
H
I
F
L
Zebra Danio
Brachydanio rerio
XP_001921139
1367
152995
A653
K
L
E
S
C
I
S
A
Q
G
D
Q
V
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122372
706
81709
I69
A
N
T
I
I
N
W
I
I
A
D
F
P
R
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190805
989
110178
T352
G
N
L
R
R
C
L
T
Q
Q
A
D
I
R
L
Poplar Tree
Populus trichocarpa
XP_002315511
1406
157649
S645
E
I
S
R
C
T
K
S
L
S
G
N
V
V
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119400
1470
164337
V646
G
I
T
S
C
I
R
V
E
G
D
K
F
T
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93
81.4
N.A.
80.8
81.3
N.A.
39.7
66.9
66.9
59.4
N.A.
N.A.
20.4
N.A.
33.3
Protein Similarity:
100
99.6
94.2
86.5
N.A.
89.6
89.8
N.A.
46.9
81.6
81.5
75.9
N.A.
N.A.
33
N.A.
49.4
P-Site Identity:
100
100
0
6.6
N.A.
66.6
60
N.A.
0
66.6
66.6
60
N.A.
N.A.
6.6
N.A.
33.3
P-Site Similarity:
100
100
6.6
33.3
N.A.
80
73.3
N.A.
20
80
66.6
80
N.A.
N.A.
6.6
N.A.
33.3
Percent
Protein Identity:
22.7
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
29
0
0
0
22
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
65
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
50
8
0
0
8
% D
% Glu:
8
0
36
0
0
0
0
0
8
0
0
0
15
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
8
8
36
0
% F
% Gly:
15
0
15
15
0
0
0
0
0
58
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
15
0
0
0
% H
% Ile:
0
15
0
8
15
43
0
8
8
0
0
0
43
0
15
% I
% Lys:
50
0
0
0
8
0
8
0
8
0
0
22
0
8
8
% K
% Leu:
8
50
8
8
8
0
36
8
15
15
0
0
8
0
58
% L
% Met:
8
0
0
0
0
15
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
8
0
0
8
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% P
% Gln:
0
8
8
0
0
0
22
0
58
15
8
36
0
0
8
% Q
% Arg:
0
0
0
15
8
0
8
0
0
0
0
0
0
15
0
% R
% Ser:
0
0
8
29
0
8
8
8
0
8
22
0
0
15
0
% S
% Thr:
0
0
22
0
0
8
8
43
0
0
0
0
8
8
0
% T
% Val:
0
0
0
0
0
15
0
8
0
0
0
0
15
8
0
% V
% Trp:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _