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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCI
All Species:
15.15
Human Site:
S972
Identified Species:
25.64
UniProt:
Q9NVI1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVI1
NP_001106849.1
1328
149324
S972
S
L
L
N
L
L
S
S
Q
E
E
D
F
N
S
Chimpanzee
Pan troglodytes
XP_001166960
1328
149462
S972
S
L
L
N
L
L
S
S
Q
E
E
D
F
N
S
Rhesus Macaque
Macaca mulatta
XP_001092590
1268
142835
E937
T
S
L
S
K
L
L
E
P
S
S
P
Q
F
V
Dog
Lupus familis
XP_545849
1234
138558
S903
S
R
L
L
E
P
S
S
P
Q
F
V
Q
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K368
1330
149307
S968
S
L
L
N
L
L
S
S
E
E
D
D
F
N
S
Rat
Rattus norvegicus
XP_001064803
1332
149518
S970
S
L
L
N
L
L
S
S
Q
E
E
D
F
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513065
736
82976
L405
I
L
S
T
L
S
K
L
L
E
T
T
S
P
Q
Chicken
Gallus gallus
NP_001108323
1338
149271
D974
N
Q
L
S
S
A
E
D
D
F
N
S
K
E
T
Frog
Xenopus laevis
NP_001164682
1337
149488
G974
S
L
I
N
Q
L
S
G
G
E
D
D
F
N
S
Zebra Danio
Brachydanio rerio
XP_001921139
1367
152995
E973
Q
L
S
G
P
E
E
E
F
N
S
K
E
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122372
706
81709
M375
S
K
N
N
A
T
A
M
W
C
I
G
S
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190805
989
110178
V658
Q
K
F
S
S
G
L
V
T
A
E
D
R
S
K
Poplar Tree
Populus trichocarpa
XP_002315511
1406
157649
I996
K
Y
E
E
A
S
R
I
D
D
Q
H
I
R
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119400
1470
164337
D974
G
L
T
G
L
L
E
D
L
L
A
V
P
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93
81.4
N.A.
80.8
81.3
N.A.
39.7
66.9
66.9
59.4
N.A.
N.A.
20.4
N.A.
33.3
Protein Similarity:
100
99.6
94.2
86.5
N.A.
89.6
89.8
N.A.
46.9
81.6
81.5
75.9
N.A.
N.A.
33
N.A.
49.4
P-Site Identity:
100
100
13.3
26.6
N.A.
86.6
100
N.A.
20
6.6
66.6
6.6
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
100
26.6
33.3
N.A.
100
100
N.A.
20
26.6
80
6.6
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
22.7
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
8
8
0
0
8
8
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
15
15
8
15
43
0
0
0
% D
% Glu:
0
0
8
8
8
8
22
15
8
43
29
0
8
15
0
% E
% Phe:
0
0
8
0
0
0
0
0
8
8
8
0
36
8
0
% F
% Gly:
8
0
0
15
0
8
0
8
8
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
8
0
0
8
0
8
0
15
% I
% Lys:
8
15
0
0
8
0
8
0
0
0
0
8
8
0
8
% K
% Leu:
0
58
50
8
43
50
15
8
15
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
8
0
8
43
0
0
0
0
0
8
8
0
0
36
0
% N
% Pro:
0
0
0
0
8
8
0
0
15
0
0
8
8
8
0
% P
% Gln:
15
8
0
0
8
0
0
0
22
8
8
0
15
0
15
% Q
% Arg:
0
8
0
0
0
0
8
0
0
0
0
0
8
8
0
% R
% Ser:
50
8
15
22
15
15
43
36
0
8
15
8
15
8
43
% S
% Thr:
8
0
8
8
0
8
0
0
8
0
8
8
0
0
8
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
15
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _