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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FANCI All Species: 9.09
Human Site: S887 Identified Species: 15.38
UniProt: Q9NVI1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVI1 NP_001106849.1 1328 149324 S887 V L L W R Y T S I P T S V E E
Chimpanzee Pan troglodytes XP_001166960 1328 149462 S887 V L L W R Y T S I P T S V E E
Rhesus Macaque Macaca mulatta XP_001092590 1268 142835 L852 S L L C L E G L Q K I F S A V
Dog Lupus familis XP_545849 1234 138558 G818 I S L L C L E G L Q K I F S A
Cat Felis silvestris
Mouse Mus musculus Q8K368 1330 149307 R883 I T R V L L W R Y T S I P T S
Rat Rattus norvegicus XP_001064803 1332 149518 R885 I T R V L F W R Y T S I P T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513065 736 82976 L320 K G K S I S L L C L E G L Q R
Chicken Gallus gallus NP_001108323 1338 149271 T889 R V L L W R Y T S I P T A V E
Frog Xenopus laevis NP_001164682 1337 149488 T889 R V L M W R Y T S I P A A A E
Zebra Danio Brachydanio rerio XP_001921139 1367 152995 N888 V L M W R Y T N V P S T V E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122372 706 81709 V290 I L C V L M S V S D I Y E D Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190805 989 110178 L573 T K S P K S L L S M A G L A N
Poplar Tree Populus trichocarpa XP_002315511 1406 157649 M911 I Y G E I K L M G P P L L K L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001119400 1470 164337 S889 C V G H I N S S L C M K E E N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93 81.4 N.A. 80.8 81.3 N.A. 39.7 66.9 66.9 59.4 N.A. N.A. 20.4 N.A. 33.3
Protein Similarity: 100 99.6 94.2 86.5 N.A. 89.6 89.8 N.A. 46.9 81.6 81.5 75.9 N.A. N.A. 33 N.A. 49.4
P-Site Identity: 100 100 13.3 6.6 N.A. 0 0 N.A. 0 13.3 13.3 60 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 13.3 20 N.A. 13.3 20 N.A. 13.3 33.3 33.3 100 N.A. N.A. 33.3 N.A. 13.3
Percent
Protein Identity: 22.7 N.A. N.A. 23.4 N.A. N.A.
Protein Similarity: 44.1 N.A. N.A. 43 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 8 8 15 22 8 % A
% Cys: 8 0 8 8 8 0 0 0 8 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 8 % D
% Glu: 0 0 0 8 0 8 8 0 0 0 8 0 15 29 29 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 8 8 0 0 % F
% Gly: 0 8 15 0 0 0 8 8 8 0 0 15 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 36 0 0 0 22 0 0 0 15 15 15 22 0 0 0 % I
% Lys: 8 8 8 0 8 8 0 0 0 8 8 8 0 8 0 % K
% Leu: 0 36 43 15 29 15 22 22 15 8 0 8 22 0 8 % L
% Met: 0 0 8 8 0 8 0 8 0 8 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 15 % N
% Pro: 0 0 0 8 0 0 0 0 0 29 22 0 15 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 8 0 0 0 8 8 % Q
% Arg: 15 0 15 0 22 15 0 15 0 0 0 0 0 0 8 % R
% Ser: 8 8 8 8 0 15 15 22 29 0 22 15 8 8 15 % S
% Thr: 8 15 0 0 0 0 22 15 0 15 15 15 0 15 0 % T
% Val: 22 22 0 22 0 0 0 8 8 0 0 0 22 8 8 % V
% Trp: 0 0 0 22 15 0 15 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 22 15 0 15 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _